恶性嗜铬细胞瘤8例  

Malignant Pheochromocytoma, Report of 8 Cases

作　　者：刘定益[1] 陈其智[1] 郑崇达[1] 王旺龙[1] 

机构地区：[1]上海第二医科大学附属瑞金医院泌尿科

出　　处：《中国肿瘤临床》1996年第10期730-733,共4页Chinese Journal of Clinical Oncology

摘　　要：报告８例恶性嗜铬细胞瘤（ＭａｌｉｇｎａｎｔｏｆｐｈｅｏｃｈｒｏｍｏｃｙｔｏｍａＭＰ），当病理发现嗜铬细胞瘤的包膜浸润，淋巴管或血管内有瘤栓并不能作为ＭＰ的证据，而良性嗜铬细胞瘤也不能完全排除ＭＰ可能。只有病理证实肿瘤播散到无副神经节的组织中才能确定ＭＰ的诊断。如能手术切除，ＭＰ可获长期的症状缓解，如不能手术切除可用α一受体阻滞剂或（１３１）Ⅰ－ＭＩＢＧ等方法治疗。From 1958 to 1994, 8 cases of well confirmed malignant pheochromocytomas (MP) were treated in our department.There seemed to be no definitive criteria differentiating malignant pheochromocytoma from benign ones clinically. biochemically, nor by imaging data. Definite vascular invasion or local infiltration by no means designates malignant pheochromocytoma. .The only ensurance of the malignant character of a pheochromocytoma is the pressence of tumor in anatomic areas where no embryologic residue of paraganglionic tissue can be found, a fact suggests metastasis. The employment of CT and (131)￣Ⅰ-MIBG is advantageous to locate the metastatic focus. The treatment of choice is complete resection of the tumor. The symptoms can be relieved by using chemotherapy or (131)￣Ⅰ-MIBG in unresectable malignant pheochromocytoma.

关 键 词：嗜铬细胞瘤 病理 治疗 

分 类 号：R736[医药卫生—肿瘤]