吸烟与非吸烟者慢性牙周炎龈下福赛类杆菌的检测  

Measuring bacteroides forsythus in smokers and non-smokers with chronic periodontitis

作　　者：王敏[1] 程政[1] 雷霆[2] 左弘[2] 

机构地区：[1]西安交通大学口腔医院,陕西西安710004 [2]西安交通大学医学院

出　　处：《临床口腔医学杂志》2006年第8期478-480,共3页Journal of Clinical Stomatology

基　　金：西安交通大学口腔医院基金资助(2004KQ05)

摘　　要：目的:利用聚合酶链反应(PCR)检测吸烟与非吸烟者龈下福赛类杆菌(Bf)水平,通过Bf的检出率进一步探讨吸烟与牙周炎的关系。方法:健康者与慢性牙周炎伴吸烟与非吸烟患者共75例,用纸捻法提取每位观察者龈沟液,PCR检测。结果:慢性牙周炎组Bf检出率(59.5%)高于健康组(24.2%),具有显著性差异(P<0.01);吸烟者慢性牙周炎组Bf检出率(72.0%)高于非吸烟者健康组、吸烟者健康组、非吸烟者慢性牙周炎组(15.8%、35.7%、41.2%),P<0.05。结论;Bf与吸烟及慢性牙周炎有密切关系。Objective.To measure Bactericides forsythus （ Bf ） in subgingival plaque samples of patients with chronic periodontitis by polymerase chain reaction （ PCR ） and to explore the correlation between the level of Bf and periodontal status. Method：A total of 75 periodontitis patients and healthy subjects cluding smokers and non-smokers , samples of one site of each patient were taken for analysis of the Bf using the polymerase chain reaction （ PCR ） method. Result： ① A significiant difference was found in detectable rate between the chronic periodontitis patients （59.5 % ）and healthy subjects （24.2%） （P〈 0.01 ）. ② Bf in smokers with chronic periodontitis （72.0 % ）was significanty higer than the other groups （15.8 % ,35.7 % ,41.2 % ） （P 〈 0.05）. Conclusion：The results suggest that Bf is relevant to the smoking and chronic periodontitis.

关 键 词：福赛类杆菌 聚合酶链反应 吸烟 慢性牙周炎 

分 类 号：R781.4[医药卫生—口腔医学]