天泰1号对阿尔茨海默病模型红细胞免疫功能的影响  

Effects of Tiantai No.1 on RBC Immunological Function in Mice Model of Alzheimer's Disease

作　　者：李明[1] 吴正治[1] 赵月仙[1] 陈嫚茵[1] 李耀芳[1] 李雪梅[1] 

机构地区：[1]深圳市第二人民医院,广东深圳518035

出　　处：《深圳中西医结合杂志》2006年第4期199-200,209,共3页Shenzhen Journal of Integrated Traditional Chinese and Western Medicine

基　　金：广东省中医药局科技计划项目(No.2060143)

摘　　要：目的研究天泰1号对阿尔茨海默病模型红细胞免疫功能的调节作用。方法将阿尔茨海默病模型动物随机分为4组,用郭氏法检测红细胞C3b受体花环率(RC3bRR)、红细胞免疫复合物花环率(RICR)、红细胞C3b受体花环促进率(RFER)及红细胞C3b受体花环抑制率(RFIR)。结果阿尔茨海默病模型RC3bRR及RFER显著降低,而RICR及RFIR显著升高;天泰1号组RC3bRR及RFER显著高于模型对照组,而RICR、RFIR显著降低。结论天泰1号可显著提高阿尔茨海默病模型的红细胞免疫功能。Objective To study the effects of Tiantai No.1 formula on RBC immunological function in mice model of Alzheimer＇s disease. Methods The Alzheimefs disease model were induced by long-term i.p.AlCl3, and the model mice were divided into 4 groups randomly. RC3bRR RICR RFER and RFIR were tested. Results In model control group, the RC3bRR and RFER were descended, meanwhile the RICR and RFIR were ascended significantly. RC3b RR and RFER were higher significantly in Tiantai No.1 group than those of model control group, RICR and RFIR were decreased significantly in Tiantai No.1 group. Conclusion Tiantai No.1 can up-regulate RBC immunological function in mice model of Alzheimer＇s disease.

关 键 词：阿尔茨海默病 红细胞免疫 天泰1号 药效学 

分 类 号：R749.16[医药卫生—神经病学与精神病学] R361.3[医药卫生—临床医学]