Oncological problems in pancreatic cancer surgery  

作　　者：Akimasa Nakao Tsutomu Fujii Hiroyuki Sugimoto Naohito Kanazumi Shuji Nomoto Yasuhiro Kodera Soichiro Inoue Shin Takeda 

机构地区：[1]Department of Surgery Ⅱ,Nagoya University Graduate School of Medicine,Nagoya,Japan

出　　处：《World Journal of Gastroenterology》2006年第28期4466-4472,共7页世界胃肠病学杂志（英文版）

摘　　要：Despite the development of more sophisticated diagnostic techniques, pancreatic carcinoma has not yet been detected in the early stage. Surgical resection provides the only chance for cure or long-term survival. The resection rate has increased due to recent advances in surgical techniques and the application of extensive surgery. However, the postoperative prognosis has been poor due to commonly occurring liver metastasis, local recurrence and peritoneal dissemination. Recent molecular-biological studies have clarified occult metastasis, micrometastasis and systemic disease in pancreatic cancer. Several oncological problems in pancreatic cancer surgery are discussed in the present review.尽管有更复杂的诊断技术的发展，胰腺的癌还没在早阶段被检测了。外科的切除术为痊愈或长期的幸存提供唯一的机会。切除术率在外科的技术和广泛的外科的申请由于最近的进展增加了。然而，手术后的预后由于通常发生的肝转移，本地复发和腹传播是差的。最近的分子生物的研究在胰腺的癌症澄清了秘密转移，微转移和系统病。在胰腺的癌症外科的几个 oncological 问题在现在的评论被讨论。

关 键 词：Pancreatic cancer Extended resection Molecular diagnosis MICROMETASTASIS Adjuvant therapy 

分 类 号：R735.9[医药卫生—肿瘤]