转移性肺癌手术治疗26例分析  

Survival after pulmonary metastasectomy: experience in 26 patients

作　　者：周永新[1] 王永武[1] 冯靖[1] 黄国长[1] 李大文[1] 

机构地区：[1]同济大学心肺疾病治疗中心

出　　处：《中国肺癌杂志》2006年第4期355-356,共2页Chinese Journal of Lung Cancer

摘　　要：背景与目的对于有手术指征的转移性肺癌患者,手术切除已成为标准的治疗方法。本研究旨在分析和评价转移性肺癌外科治疗的疗效及适应证。方法回顾性分析我院1991年11月至2003年5月手术治疗的26例转移性肺癌病例,其中男12例,女14例,平均年龄50岁。肿瘤来源于全身各组织器官。其中5例同时合并肝或脑转移。结果全组无围术期死亡,全肺切除4例,肺叶切除8例,肺楔形切除14例(其中8例在胸腔镜结合小切口下行手术切除)。平均随访5.1年,随访率为96.2%,1、2、5年生存率分别为69.2%(18/26)、42.9%(9/21)、27.3%(3/11)。结论对于符合手术指征的转移性肺癌患者应尽可能手术治疗,肝、脑也同时有可切除转移灶的患者可分期行手术切除,对于明确为单发转移的患者可在胸腔镜结合小切口下行手术切除。Background and objective Surgical resection becomes standard treatment for pulmonary metastatic tumor with operative indication. The aim of this study is to analyze the indication and surgical efficacy of pulmonary metastasectomy. Methods From November 1991 to May 2003, a total of 26 patients with pulmonary metastatic tumors were treated surgically in our hospital, 12 cases were males and 14 females, with an average age of 50 years old. The metastatic tumors came from different organs and tissues, 5 cases accompanied by metastatic lumors of liver or brain. Results Four cases underwent pneumonectomy, 8 lobectomy, and 14 wedge resection （in which 8 cases underwent mildly invasive operation using video-assisted thoracic surgery）. No operative death occurred. 5 year survival rate was 27.3% （3/11）, 2-year survival rate 42.9% （9/21） and 1-year survival rate 69.2% （18/26）. Conclusion Pulmonary metastasectomy is recommended in pulmonary metastases with operative indication, and is still effective in cases accompanied by resectable metastatic tumors of liver or brain. Mildly invasive operation using video-assisted thoracic surgery might be chosen for some cases with single metastatic locus.

关 键 词：肺肿瘤 转移 外科 胸腔镜 

分 类 号：R734.2[医药卫生—肿瘤]