顶复门寄生虫顶质体的研究进展  

Advances in apicoplast of apicomplexan parasites

作　　者：张维[1] 刘群[1] 

机构地区：[1]中国农业大学动物医学院,北京100094

出　　处：《中国兽医科学》2006年第8期674-678,共5页Chinese Veterinary Science

摘　　要：从顶质体的发现、起源、形态学、基因组以及生物学功能等方面介绍了顶复门寄生虫顶质体的一些研究进展,说明了顶质体对于顶复门寄生虫的存活具有十分重要的作用,它参与了脂肪酸、血红素以及类异戊二烯的生物学合成。提示,顶质体所具有的新陈代谢功能也使其成为研制抗寄生虫药的潜在靶位点。Advances in apicoplast of apicomplexan parasites were reviewed on its discovery, origin, morphology, genome and functions. It was considered that the apicoplast may play an important role in parasite＇s maintenance, and participate in biosynthesis of fatty acid, heme and isoprenoids. The metabolic processes of the apicoplast present potential therapeutic targets for drug development.

关 键 词：顶复门寄生虫 顶质体 内共生 刚地弓形虫 恶性疟原虫 

分 类 号：S852.72[农业科学—基础兽医学]