米氮平与氟西丁治疗老年抑郁症患者的对照研究  

Comparative Study of Mirtazapine and Fluoxetine in the Treatment of Senile Depression

作　　者：朱金富[1] 

机构地区：[1]中国.河南新乡医学院心理学系,453003

出　　处：《中国健康心理学杂志》2006年第5期546-547,共2页China Journal of Health Psychology

基　　金：河南省高校创新人才资助项目(编号2004294)

摘　　要：目的探讨米氮平治疗老年抑郁症患者的疗效和副反应。方法46例符合CCMD-3抑郁症诊断标准的年龄>60岁老年抑郁症患者,应用米氮平和氟西丁各23例进行随机对照研究,观察6周,采用汉密顿抑郁量表(HAMD)和副反应量表(TESS)观察患者对治疗的疗效和副反应的变化。结果两种药物疗效相仿,米氮平起效快,副反应少。结论米氮平治疗老年抑郁症患者安全有效,副反应小。Objective To explore the efficacy and side effects of mirtazapine and fluoxetine in the treatment of senile depression. Methods 46 senile depression patients according to CCMD-- 3, whose ages were more than 60 years old, were randomly divided into mirtazapine group （n = 23） and fluoxetine group （n= 23） for 6 weeks. Hamilton depression scale （HAMD）, treatment emergent symptom scale （TESS） were adopted to evaluate the clinical efficacy and side effects. Results Two drugs had similar efficacy, but mirtazapine took effects more quickly. The side effect was fewer. Conclusion Mitazapine in the treatment of senile depression patients is a safe and effective antidepressant and side effects is fewer.

关 键 词：米氮平 氟西丁 老年抑郁症 副反应量表 

分 类 号：R749.4[医药卫生—神经病学与精神病学] R969.4[医药卫生—临床医学]