力肽对胃肠道肿瘤患者围手术期作用的前瞻性研究  

The effects of Dipeptiven in the surgical patients with gastrointestinal cancer

作　　者：严俊[1] 周东[1] 

机构地区：[1]福建省肿瘤医院腹部外科,350014

出　　处：《福建医药杂志》2006年第4期16-18,共3页Fujian Medical Journal

摘　　要：目的前瞻性研究力肽对胃肠道肿瘤患者围手术期的作用。方法40例胃肠道肿瘤患者,随机分为两组,每组20人,对照组围手术期营养支持,实验组围手术期在营养支持基础上加用力肽,术前2天及术后7天抽血,应用流式细胞仪检测免疫指标CD3、CD4、CD8、CD4/CD8,并对比两组患者术后7天体重、肠道恢复时间、住院时间、住院费用。结果对照组和实验组术前2天体重及CD3+、CD4+、CD8+、CD4+/CD8+无显著性差异(P>0.05);术后7天体重及CD3+、CD4+、CD8+、CD4+/CD8+、术后肠道恢复时间、住院时间有显著性差异(P<0.05);住院费用无显著性差异(P>0.05)。结论力肽可提高胃肠道肿瘤患者围手术期细胞免疫功能,促进肠道恢复,利于患者早日康复。Objective To investigate the effects of Dipeptiven in patient with gastrointestinal cancer during the operation. Methods Fourty surgical patients were divided into two groups at random. The control group was treated with parenteral nutrition after operation and the Dipeptiven group was treated with dipeptiven basing on parenteral nutrition. The Immune function data of CD3, CD4, CD,, CD4/CD8 and the recover time, the cost in hospital were analysed. Results The CD3, CD4, CD4/ CD8 in the Dipeptiven group were higher than those in the control group （P〈0.05）. The recover time was shorter in the Dipeptiven group. Conclusion Dipeptiven can improve Immune function in the surgical patient with gastrointestinal cancer.

关 键 词：力肽 胃肠外营养 免疫功能 胃肠道肿瘤 

分 类 号：R735[医药卫生—肿瘤]