瑞诺组织补片植入动物拔牙窝的实验观察  

The animal laboratory on the induction of the fiber tissue slice in reparative alveolar bone after teeth extraction

作　　者：冯力 廖兵飞 张国志 陈灼怀 张锦中 范海东 胡杰[2] 

机构地区：[1]广东省深圳市人民医院,518020 [2]清华大学生命科学院

出　　处：《中国现代医药杂志》2006年第8期7-9,共3页Modern Medicine Journal of China

基　　金：广东省深圳市科技基金资助项目(JH200507131133A)

摘　　要：目的观察瑞诺纤维组织补片对拔牙窝缺损修复的引导作用。方法建立狗拔牙创的动物模型,一侧拔牙创为实验组,将脱细胞纤维组织补片植入实验组,另一侧同名牙位的拔牙创为对照组,拔牙后按常规处理缝合创面。分别于术后5天、2周、1个月、2个月、3个月处死,利用双能X线骨密度测量仪和螺旋CT观察拔牙创骨愈合。结果骨密度观察:2周、1个月、2个月时实验组成骨明显快于对照组;螺旋CT三维重建:实验组牙槽嵴较为丰满,对照组的牙槽嵴有明显吸收。结论脱细胞纤维组织补片对成骨具有较强地引导作用。Objective To study the induction of the acellular fiber tissue matrix in bone repairing process alveolar bone defect after teeth extraction. Methods Established dog pattern of teeth extraction socket. One side of teeth extraction socket which was filled with fiber tissue slice was experimental group. Another side which was same teeth extraction socket was control group, The peripheral tissue coating alveolar bone was harvested for histopathologic study after 5 days, 2 weeks, 1 month and 3 months. Results The main histopathologic changes： bone mineral density（BMD）：experimental group was significantly higher than control group. Conclusion The fiber tissue slice can induce alveolar bone regeneration.

关 键 词：瑞诺纤维组织补片 牙槽骨 动物实验 成骨细胞 

分 类 号：R782[医药卫生—口腔医学]