心脏恶性纤维组织细胞瘤1例  

CARDIAL MALIGNANT FIBROUS HISTIOCYTOMA:A REPORT OF 1 CASE

作　　者：刘巧玲 张晓晖[2] 晏培松[2] 张传山[2] 李青[2] 马福成[2] 

机构地区：[1]广东省佛山市南海区卫生职业技术学校病理教研室,528000 [2]陕西西安第四军医大学西京医院病理科

出　　处：《中国煤炭工业医学杂志》2006年第11期1235-1236,共2页Chinese Journal of Coal Industry Medicine

摘　　要：目的报告1例罕见的心脏恶性纤维组织细胞瘤,结合文献复习,讨论心脏恶性纤维组织细胞瘤的临床病理特点。方法通过组织学方法,对1例心脏恶性纤维组织细胞瘤的组织学形态进行观察,并进行了特染、免疫组织化学染色和电镜的研究。结果患者左房内房间隔上可见一占位病变。体积10cm×3cm×9cm。显微镜下见肿瘤组织由梭形、卵圆形及多核细胞组成,异型性明显,核分裂多见。特殊染色:PAS(+)、AB(+)。免疫组化:CD68(+)、α-AT(±)、CEA(-)、KER(-)。电镜结果:瘤组织由多种细胞成分组成,以纤维母细胞为主。支持恶性纤维组织细胞瘤诊断。结论原发心脏恶性纤维组织细胞瘤是一种非常罕见的心脏原发恶性肿瘤,具有一定的临床病理特点。Objective To report 1 case with cardial malignant fibrohistiocytoma, and discuss its clinical pathological features based on literature review. Methods Histology features had been observed in the case with cardial malignant fibrohistiocytoma, and special staining, immunohistochemistry and electron microscope studies were also performed, Results The patient was a 42 - year- old female, there was a tumor with volume of 10 × 3 × 9cm in interauricular septum of the left atrium, The tumor was consisted of spindle, oval and polynucleate cells, with an obvious atypia and many mitosis figures. Special staining showed negative for PAS and alcian blue, lmmunohistochemistry results were CD68 （ ＋ ）, α - AT （ -＋ ）, CEA（ - ）, KER（ - ）. Electron microscophs revealed that the tumor was consisted of various cells including fibroblast, which indicated a diagnosis of malignant fibrohistiocytoma. Conclusion Primary malignant histlocytoma is rare in heart which contains clinical pathological characteristics.

关 键 词：心脏 恶性纤维组织细胞瘤 病理检查 

分 类 号：R732.1[医药卫生—肿瘤]