皮肤神经内分泌腺瘤:一少见肿瘤  

Cutaneous neuroendocrine adenoma: An uncommon neoplasm

作　　者：Mahalingam M. Kveaton J.F. Bhawan J. 冯义国 

机构地区：[1]Umass Memorial Medical Center,Memorial Campus, 119 Belmont Street, Worcester, MA 01605, United States Dr.

出　　处：《世界核心医学期刊文摘（皮肤病学分册）》2006年第8期7-8,共2页Digest of the World Core Medical JOurnals:Dermatology

摘　　要：Background: Cutaneous neuroendocrine neoplasms are typically malignant. Benign cutaneous neuroendocrine tumors are uncommon. Methods: We report the case of a 32-year-old female who presented with a granular mass in the right external auditory canal. Results: Microscopic examination of a shave biopsy revealed a poorly circumscribed neoplasm with glandular differentiation. While cytologic atypia and mitotic activity were not evident, pagetoid spread was observed. Immunohistochemistry was indicative of neuroendocrine origin. Conclusions: This case report of neuroendocrine adenoma indicates that this entity should be entertained in the repertoire of conditions affecting the external ear.Background： Cutaneous neuroendocrine neoplasms are typically malignant. Benign cutaneous neuroendocrine tumors are uncommon. Methods： We report the case of a 32-year-old female who presented with a granular mass in the right external auditory canal. Results： Microscopic examination of a shave biopsy revealed a poorly circumscribed neoplasm with glandular differentiation. While cytologic atypia and mitotic activity were not evident, pagetoid spread was observed. Immunohistochemistry was indicative of neuroendocrine origin. Conclusions： This case report of neuroendocrine adenoma indicates that this entity should be entertained in the repertoire of conditions affecting the external ear.

关 键 词：内分泌腺瘤 皮肤神经 少见肿瘤 神经内分泌肿瘤 PAGET样 显微镜检查 内分泌源性 恶性肿瘤 女性患者 免疫组化 

分 类 号：R736[医药卫生—肿瘤] R337[医药卫生—临床医学]