口腔恶性黑色素瘤伴假上皮瘤样增生1例  

Oral malignant melanoma associated with pseudoepitheliomatous hyperplasia. Report of a case

作　　者：Meleti M. Mooi W.J. Van Der Waal I. 党倩丽 

机构地区：[1]Vrije Universiteit Medical Center/ACTA, PO Box 7057, 1107, MB, Amsterdam, Netherlands Dr.

出　　处：《世界核心医学期刊文摘（皮肤病学分册）》2006年第8期9-9,共1页Digest of the World Core Medical JOurnals:Dermatology

摘　　要：Background: Pseudoepitheliomatous hyperplasia (PEH), a histological mimic of squamous cell carcinoma, is an exuberant reactive epithelial proliferation that may be induced by a variety of infectious, traumatic, inflammatory and neoplastic conditions of the skin and mucous membranes. PEH has been described in association with Spitz nevi and intramucosal nevi but not with oral malignant melanoma. Methods and results: A case of PEH in malignant melanoma of the palate in a 46-year-old female patient has been described. A search of the English literature did not disclose any previously reported case of such event. Conclusions: PEH associated with oral malignant melanoma is apparently very rare and most likely originates from the surface epithelium. This is in contrast with PEH in cutaneous melanoma where follicular or eccrine units have been suggested to be the origin.Background： Pseudoepitheliomatous hyperplasia （ PEH）, a histological mimic of squamous cell carcinoma, is an exuberant reactive epithelial proliferation that may be induced by a variety of infectious, traumatic, inflammatory and neoplastic conditions of the skin and mucous membranes. PEH has been described in association with Spitz nevi and intramucosal nevi but not with oral malignant melanoma. Methods and results： A case of PEH in malignant melanoma of the palate in a 46-year-old female patient has been described. A search of the English literature did not disclose any previously reported case of such event. Con clusions： PEH associated with oral malignant melanoma is apparently very rare and most likely originates from the surface epithelium. This is in contrast with PEH in cutaneous melanoma where follicular or eccrine units have been suggested to be the origin.

关 键 词：口腔恶性黑色素瘤 假上皮瘤样增生 SPITZ痣 皮肤黑色素瘤 女性患者 鳞状细胞癌 炎症反应 病例报道 

分 类 号：R739.85[医药卫生—肿瘤] R644[医药卫生—临床医学]