新加坡亚洲人的基底细胞癌特征及完全与不完全切除肿瘤的比较  

Characteristics of basal cell carcinoma amongst Asians in Singapore and a comparison between completely and incompletely excised tumors

作　　者：Goh B.K. AngP. Wu Y.J. Goh C.L. 潘敏(译) 

机构地区：[1]National Skin Centre, 1 Mandalay Road, Sin gapore 308205, Singapore -INT. J. DERMATOL 2006, 45/5 (561 -564) [2]不详

出　　处：《世界核心医学期刊文摘（皮肤病学分册）》2006年第8期34-35,共2页Digest of the World Core Medical JOurnals:Dermatology

摘　　要：Background: Most published series of basal cell carcinomas (BCCs) are based on Caucasian populations. Very little is known about the characteristics of incompletely excised BCCs in Asians. Objectives: This study examines the characteristics of BCCs in Asian residents in Singapore, and compares incompletely with completely excised tumors after conventional surgical excision. Patients and Methods: A retrospective study was conducted using the case records of patients who had a primary BCC excised at the National Skin Centre between 1991 and 1995. Results: A total of 185 histologically confirmed BCCs were recorded in 166 patients (male to female ratio, 0.95; mean age, 70.9 years). The highest proportion (27.1% ) was in the 81-90-year age group. Compared with census data, a significantly higher proportion of patients with BCCs were Chinese (P < 0.001). The tumors averaged 12.0 mm in diameter and the majority (84.3% ) were located on the head and neck. In 28 lesions (15.1% ), the tumors were incompletely excised, with those on the nose and nasolabial folds being most frequent. Incompletely excised BCCs were more likely than completely excised lesions to be located on the mid- face and trunk (P = 0.003), but there was no significant correlation with tumor size, tumor duration, or patient age, race, and gender. The overall recurrence rate was 1.6% over a mean follow-up time of 74 months. Conclusions: BCCs are more common amongst Chinese in Singapore and occur chiefly in the elderly. Conventional surgical excision with margin control achieves a satisfactory tumor clearance rate of 84.9% . Incomplete excision is associated with tumor location on the mid-face and trunk rather than tumor size or duration.Background： Most published series of basal cell carcinomas （BCCs） are based on Caucasian populations. Very little is known about the characteristics of incompletely excised BCCs in Asians. Objectives： This study examines the characteristics of BCCs in Asian residents in Singapore, and compares incompletely with completely excised tumors after conventional surgical excision. Patients and Methods： A retrospective study was conducted using the case records of patients who had a primary BCC excised at the National Skin Centre between 1991 and 1995. Results： A total of 185 histologically confirmed BCCs were recorded in 166 patients （male to female ratio, 0.95; mean age, 70.9 years） . The highest proportion （27.1%） was in the 81-90-year age group. Compared with census data, a significantly higher proportion of patients with BCCs were Chinese （P 〈 0. 001）. The tumors averaged 12.0 mm in diameter and the majority （84. 3% ） were located on the head and neck. In 28 lesions （15. 1% ）, the tumors were incompletely excised, with those on the nose and nasolabial folds being most frequent. Incompletely excised BCCs were more likely than completely excised lesions to be located on the mid-face and trunk （P = 0. 003）, but there was no significant correlation with tumor size, tumor duration, or patient age, race, and gender. The overall recurrence rate was 1.6% over a mean follow-up time of 74 months. Conclusions： BCCs are more common amongst Chinese in Singapore and occur chiefly in the elderly.

关 键 词：肿瘤切除术 基底细胞癌 完全切除 亚洲人 新加坡 患者年龄 平均年龄 研究调查 切除术后 普查资料 

分 类 号：R739.41[医药卫生—肿瘤] R739.5[医药卫生—临床医学]