前额迟发性小汗腺血管瘤性错构瘤  

Late-onset eccrine angiomatous hamartoma on the forehead

作　　者：Jeong E. Park H.J. Oh S.T. 李政霄 

机构地区：[1]Department of Dermatology, College of Medicine, Catholic University of Korea, 62 Youido-dong, Youngdeungpo-ku, Seoul 150- 713, South Korea Dr.

出　　处：《世界核心医学期刊文摘（皮肤病学分册）》2006年第8期38-38,共1页Digest of the World Core Medical JOurnals:Dermatology

摘　　要：A 71-year-old Korean man presented with a solitary erythematous plaque on his forehead (Fig. 1). It was first noticed by the patient 1 year previously and had slowly increased in size over that time. Physical examination revealed a slightly elevated, 1.5 cm × 1.5 cm erythematous plaque on the upper midline of the forehead. Sweating was not evoked by physical work or emotional stress. There was no pain or tenderness associated with the lesion. The patient had no history of trauma to the forehead. Histopathologic examination of the lesion showed increased numbers of eccrine glands, as well as dilated vascular channels in the deep dermis and subcutaneous tissue (Fig. 2). An immunohistochemical study showed that these eccrine glands stained positively for S- 100 and carcinoembryonic antigen (CEA), and the vascular channels for the antifactor VIII-related antigens. These findings are consistent with eccrine angiomatous hamartoma. There was no change in the lesion during the 1-year follow-up period.A 71-year-old Korean man presented with a solitary erythematous plaque on his forehead （Fig. 1 ） . It was first noticed by the patient 1 year previously and had slowly increased in size over that time. Physical examination revealed a slightly elevated, 1.5 cm ×1.5 cm erythematous plaque on the upper midline of the forehead. Sweating was not evoked by physical work or emotional stress. There was no pain or tenderness associated with the lesion. The patient had no history of trauma to the forehead. Histopathologic examination of the lesion showed increased numbers of eccrine glands, as well as dilated vascular channels in the deep dermis and subcutaneous tissue （Fig2） . An immunohistochemical study showed that these eccrine glands stained positively for S - 100 and carcinoembryonic antigen （CEA）, and the vascular channels for the antifactor Ⅷ-related antigens. These findings are consistent with eccrine angiomatous hamartoma.

关 键 词：血管瘤性错构瘤 小汗腺 前额 迟发性 癌胚抗原(CEA) 第Ⅷ因子相关抗原 组织病理检查 免疫组化检查 外分泌腺 应激反应 

分 类 号：R739.5[医药卫生—肿瘤] R443.1[医药卫生—临床医学]