食管癌微血管密度的检测及临床意义  

Clinical significance of microvascular density in esophageal carcinoma

作　　者：张晓飞[1] 刘艳梅[1] 丛旭滋[2] 刘立群[3] 

机构地区：[1]山东省苍山县人民医院,山东苍山277700 [2]山东大学齐鲁医院,山东济南250002 [3]潍坊医学院附属医院,山东潍坊261031

出　　处：《现代肿瘤医学》2006年第9期1074-1076,共3页Journal of Modern Oncology

摘　　要：目的:观察微血管密度(MVD)在判断食管癌患者预后方面的价值,为临床综合治疗提供依据。方法:以我院手术治疗的81例食管癌患者为研究对象,用免疫组化法检测肿瘤标本的微血管密度,并分析该指标在判断预后方面的价值。结果:食管癌MVD与年龄、肿瘤大小无关,与淋巴结状况及TNM分期显著相关,MVD与TNM分期都是危险因子,表达越高,生存期越短。结论:MVD是食管癌的独立预后因子。Objective：To erplove the prognostic value of microvascular density （MVD） in esophageal cancer. Methods： MVD of 81 esophageal carcinoma patients were tested for MVD by means of immunohistochemical motheds. Results： Lymph node status and TNM stage were significantly correlated with the MVD. MVD and TNM stage were risk factors for the survival of esophagcal cancer patients. Conclusion： MVD may be independent prognostic factor for esophageal carcinoma.

关 键 词：食管癌 微血管密度 免疫组织分学法 

分 类 号：R735.1[医药卫生—肿瘤]