妊娠期肝内胆汁淤积症的脐动脉超声多普勒变化  

Variations of Doppler ultrasonic parameters of fetal umbilical artery in pregnant women with intrahepatic cholestasis

作　　者：梁青[1] 邓学东[1] 殷林亮[1] 

机构地区：[1]苏州市立医院母子保健中心超声科,江苏苏州215002

出　　处：《中国医学影像技术》2006年第8期1233-1235,共3页Chinese Journal of Medical Imaging Technology

摘　　要：目的评价彩色多普勒血流成像检测妊娠期肝内胆汁淤积症(ICP)胎儿血流动力学变化在预测围产儿预后中的价值。方法应用彩超检测119例孕36～40周ICP孕妇及544例同孕周正常孕妇的胎儿脐动脉超声多普勒变化,测出脐动脉血流收缩期峰值(S)与舒张期末流速(D)的比值(S/D)、搏动指数(PI)和阻力指数(RI)值,两者进行比较。结果单纯ICP组与正常妊娠组比较,S/D、PI和RI无统计学差异,而ICP并发胎儿宫内窘迫时与正常组比较,S/D有差异,PI和RI无差异;ICP脐动脉多普勒检查阻力升高者出现胎儿窘迫的敏感性为42.9%,特异性为89.4%,阳性预测值47.4%。结论彩色多普勒超声监测ICP胎儿脐动脉多普勒测定为临床早期诊断胎儿窘迫提供可靠依据。Objective To investigate fetal hemodynamics in intrahepatic cholestasis of pregnancy （ICP） using color Doppler flow imaging （CDFI）. Methods By using color Doppler flow image technique, systolic/diastolic （S/D）, pulse index （PI） and resistance index （RI） were measured in 119 cases of pregnant women with intrahepatic cholestasis during 36-40 weeks, and they were compared with 544 cases in normal pregnant women with the same pregnant week. Results There was no statistics significance by comparing the group in simply ICP with the normal group. S/D was different by comparing the group in ICP complicated with fetal distress with the normal group, although PI and RI had no statistics significance. When S/D increased in ICP, it prompted fetal distress. Its sensitivity was 42.9%, specificity was 89.4% and positive predictive value （PPV） was 47.4%. Conclusion The Doppler ultrasonic of umbilical artery could provide reliable evidence for early clinical diagnosis of fetal distress.

关 键 词：胆汁淤积 肝内 胎儿窘迫 超声检查 多普勒 脐动脉 

分 类 号：R575[医药卫生—消化系统] R445.1[医药卫生—内科学]