原发性结直肠淋巴瘤20例临床分析  

Clinical analysis of 20 cases of primary colorectal lymphoma

作　　者：段伦喜[1] 赵华[1] 刘国清[1] 李铁钢[1] 钟德玝[1] 陈勇[1] 胡辅珍[1] 皮执民[1] 周均[1] 雷三林[1] 

机构地区：[1]中南大学湘雅二医院普通外科,湖南长沙410007

出　　处：《中国普通外科杂志》2006年第8期602-605,共4页China Journal of General Surgery

摘　　要：目的探讨原发性结直肠淋巴瘤的诊断及临床病理、治疗与生存预后的关系。方法回顾性总结3 4年间因原发性结直肠淋巴瘤接受手术治疗者的临床资料;分析治疗和各临床病理因素对预后的影响。结果肿瘤大小、淋巴结转移、有无邻近器官侵犯和远处转移、治疗方式对患者生存预后具有显著性意义(P<0.0 1);年龄、性别、肿瘤单发或多发、淋巴瘤组织细胞恶性程度、肿瘤侵犯深度不是影响患者预后的独立因素(P>0.0 5)。结论原发性结直肠淋巴瘤手术前误诊率高。治疗应以手术切除为主。根治手术辅以化疗可以获得较好的预后。Objective To investigate the diagnosis and the relationship between its clinicopathological characteristics, treatment and the prognosis of primary colorectal lymphoma. Methods The clinical data of 20 primary colorectal lymphoma patients who received operative treatment in the past 34 years in our hospital were retrospectively summarized , and the influence of treatment and each clinicopathological factor on prognosis was assessed. Results Tumor size, lymph node metastasis, invasion of neighboring organs and distant metastasis , and type of operative treatment were significantly related to the survival （ P 〈 0.01 ） . Age, sex, single or multiple tumors, degree of cell malignancy in lymphoma tissues and depth of tumor invasion were not independent factors of prognosis （ P 〉 0.05 ） . Conclusions Diagnosis of primary colorectal lymphoma before operation is difficult, and misdiagnosis is common. Operative treatment is the main therapeutic means for colorectal lymphoma. Radical operation combined with chemotherapy can gain a good prognosis.

关 键 词：结直肠肿瘤/病理学 淋巴瘤/病理学 

分 类 号：R735.3[医药卫生—肿瘤]