拉呋替丁的波谱学数据和结构确证  

Spectroscopic Data Derived Structure of Lafutidine

作　　者：赵如胜[1] 杨日芳[1] 恽榴红[1] 刘河[1] 

机构地区：[1]军事医学科学院毒物药物研究所,北京100850

出　　处：《波谱学杂志》2006年第3期313-319,共7页Chinese Journal of Magnetic Resonance

摘　　要：对拉呋替丁的氢谱(1HNMR)、碳谱(13CNMR,DEPT)、异核多键相关谱(HMBC)予以解析并进行了报道,对其所有的1HNMR和13CNMR谱信号进行了归属;讨论了红外特征吸收,热差和热重分析;质谱的裂解途径和离子特征也与拉呋替丁的分子结构相符.Mass spectrum and one-dimensional （^1H and ^13C ） and two-dimensional （heteronuclear multiple-bond coherence, HMBC） NMR spectra of lafutidine were reported and interpreted. The ^1H and ^13C chemical shifts were assigned. The spectroscopic characteristics of the compound were discussed in detail and found to be consistent with its structure known previously.

关 键 词：核磁共振 质谱 归属 拉呋替丁 

分 类 号：O641[理学—物理化学]