脑动脉粥样硬化和脑血栓者血浆D－二聚体检测及临床意义  

The Clinical significance of measurement of plasma D dimer in patients with cerebral atherosclerosis and atherothrombotic stroke

作　　者：郭宗君[1] 石秉霞[1] 金丽英[1] 

机构地区：[1]青岛医学院脑血管病研究所

出　　处：《实用老年医学》1996年第6期260-261,共2页Practical Geriatrics

摘　　要：检测３２例脑动脉粥样硬化和２８例脑血栓病人血浆Ｄ－二聚体含量，并与３３例年龄匹配的健康人（对照组）比较。结果Ｄ－二聚体含量在对照组为０．４３±０．２６ｍｇ／Ｌ；脑动脉粥样硬化组与脑血栓形成组（病后＜７ｄ、４ｗ、６ｗ３个时期）血浆Ｄ－二聚体含量分别为０．８６±０．４８、１．０２±０．９７、１．０７±１．０４和１．０５±０．８７ｍｇ／Ｌ，与对照组相比均明显升高（Ｐ均＜０．００１），但脑动脉粥样硬化和脑血栓形成两组之间无显著差异（Ｐ＞０．０５）。认为Ｄ－二聚体可作为检测血栓前状态和病情判断的指标。The plasma concentrations of D dimer were measured in 32 cases of cerebral atherosclerosis and 28 cases of atherothrombotic stroke,and were compared with those of 33 controls.A marked elevation of plasma concentrations of D dimer were observed in cerebral atherosclerosis and in atherothrobosis at all periods ( P <0 001) as compared with the controls.No significant difference was found between the data of these 2 groups.D dimer may be used as a marker to detect the prothrombosis state and to judge the condition of the illness.

关 键 词：脑动脉粥样硬化 脑血栓形成 血浆D-二聚体 

分 类 号：R743.1[医药卫生—神经病学与精神病学]