富血小板血浆在颌面部非血管化骨移植中的应用  

APPLICATION OF PLATELET-RICH PLASMA IN NON-VASCULARIED BONE GRAFT OF MAXILLOFACIAL SURGERY

作　　者：冯扬[1] 唐休发[1] 

机构地区：[1]四川大学华西口腔医院颌面外科,成都610041

出　　处：《中国修复重建外科杂志》2006年第9期944-946,共3页Chinese Journal of Reparative and Reconstructive Surgery

摘　　要：目的对近年来国内外有关富血小板血浆(platelet-richplasma,PRP)促进骨形成的作用和在颌面部非血管化骨移植中的应用进行综述。方法广泛查阅相关文献,对PRP促进骨形成作用机制进行综合分析。结果PRP应用于非血管化骨移植中有促进新骨形成的作用,其机制可能与血小板本身含有各类细胞因子相关。且已有学者将其应用于临床颌面部骨缺损修复,并取得较好效果。结论PRP存在可能的促新骨形成作用,但其具体作用机制、作用持续时间以及效应与浓度的关系仍有待进一步的研究。Objective To introduce the application of platelet-rich plasma （PRP） in non vascularised bone grafts （NVIAG） of maxillofacial surgery and its potential mechanism in recent years. Methods The latest articles were extensively retrieved, and the potential mechanism for PRP promotes the osteogenesis was discussed. Results PRP promotes osteogenesis when applied to NVBG, and the cytokine included in platelet is thought to be the ingredient for PRP＇s effect. Some scholar has already applied PRP in the restoration of maxillofacial bone defect and got good results. Conclusion PRP has the potential to promotes osteogenesis, and more studies are needed for further understanding of its mechanism.

关 键 词：富血小板血浆 非血管化骨移植 修复 

分 类 号：R782[医药卫生—口腔医学]