孤立性颅内粒细胞肉瘤1例并文献复习  

Isolated Intracranial Granulocytic Sarcoma: a Case Report and Review of the Literatures

作　　者：梅文忠[1] 林志雄[1] 何理盛[1] 林震涛[1] 

机构地区：[1]福建医科大学附属第一医院神经外科,福建福州350005

出　　处：《中国神经肿瘤杂志》2006年第2期104-106,共3页Chinese Journal of Neuro-Oncology

摘　　要：背景与目的:颅内孤立性粒细胞肉瘤较罕见,本文旨在探讨了解孤立性颅内粒细胞肉瘤的诊断、鉴别诊断及治疗原则。方法:回顾性分析1例孤立性颅内粒细胞肉瘤患者的临床资料,并复习相关文献进行讨论。结果:左额叶肿瘤术前误诊为脑膜瘤。行手术全切除,肿瘤累及硬脑膜及临近额眶骨,术后免疫组化确诊粒细胞肉瘤。外周血象及骨髓涂片正常。术后配合局部放射治疗。随访6个月无复发,外周血象无异常。结论:孤立性颅内粒细胞肉瘤临床罕见,易误诊为脑膜瘤或恶性淋巴瘤。确诊依靠病理学及免疫组化。手术切除为首选治疗方法。对局部浸润可配合放疗,而外周血象及骨髓涂片正常者不宜常规化疗,宜长期随访并监测血象,注意出现髓系白血病的可能。BACKGROUND ＆ OBJECTIVE： Isolated intracranial granulocytic sarcoma is rare. This artical, through reviewing a recent treated case, discussed diagnosis, differential diagnosis and therapeutic principle of isolated intracranial granulocytic sarcoma. METHODS：Case report and review of the literatures. RESULTS： We reported a case of isolated granulocytic sarcoma in the left frontal region ocuring in a 38 years old man. The patient completed radiotherapy after surgical removal and he remained diseasefree in six months follow-up. The final diagnosis of granuloeytie sarcoma was established by histopathology and immunohistochemical studies. The differential diagnosis of this tumor including meningioma and malignant lylnphoma. Surgical removal is the best option for progressive disease. Adjuvant radiotherapy is advised for infiltrative residual. However chemotherapy is not nessesary for isolated intraeranial granulocytie sarcoma. However, Monitoring of blood white cell count is advised for the risk of development of leukaemia.

关 键 词：粒细胞肉瘤 颅内 诊断 治疗 

分 类 号：R739.41[医药卫生—肿瘤]