藤茶抗炎作用的实验研究  

The experimental study of cane tea on anti-inflammation action in mice

作　　者：林萍[1] 伍扬[1] 

机构地区：[1]湖北民族学院医学院,湖北恩施445000

出　　处：《四川中医》2006年第9期12-14,共3页Journal of Sichuan of Traditional Chinese Medicine

摘　　要：目的:研究藤茶的抗炎及免疫调节作用。方法:将小鼠随机分为对照组、阳性药物组和实验组,用2,4-二硝基氯苯(DNCB)诱导小鼠肠迟发过敏反应及结肠炎症和溃疡,然后用藤茶水提取物灌胃治疗结肠炎;观察疾病活动指数、结肠大体和镜下改变;采用角叉莱胶致足肿胀实验方法,对藤茶水提物的抗炎作用进行了研究。结果:藤茶水提物在所试剂量范围内(2g、4g、8g生药/k/d)具有较明显的抗炎作用,特别是大、中剂量组的疾病活动指数、组织病理学评分均显著降低(P<0.01);足肿胀明显减轻(P<0.01)。结论:藤茶水提取物有抗炎及免疫调节作用。此实验为藤茶的临床应用提供了理论依据。Objective： To investigate the cane tea anti-inflammation and immunity control action. Methods： 50 mice were randomly divided into control group, the positive drng group and the experimental group. The mice were induced intestine delayed allergic reaction, the colon inflammation and ulcer by 2, 4-dinitrochlorobenzol （DNCB）, then treated colitis with the cane tea extraction by perfusing stomach. Observed disease activity index, the colon change under macro-and microscope; Also observed the effect of cane tea extraction on anti-inflammation by the way of using jiao cha000 to induce feet swelling in mice. Results： The cane tea extraction responsible for the anti - inflammation effect in the dose range （2g, 4g, 8g crude drugs/K/D）, particularly the disease activity index and pathological score decreased significantly in the big, the middle dose group. （ P 〈 0.01） ; The feet swelling obviously reduce （ P 〈 0.01 ） . Conclusions ： The cane tea extraction have performed the anti-inflammation and the immunity control action. This experiment has provided the theory basis for the clinical usage of the cane tea.

关 键 词：抗炎 藤茶 小鼠 

分 类 号：R285.5[医药卫生—中药学]