中心静脉导管引流联合胞必佳治疗恶性胸腔积液疗效观察  

Effects of central venous catheter combined with N-CWS on treating malignant pleural effusion

作　　者：王瑾[1] 胡斌[1] 丁红梅[1] 

机构地区：[1]安徽省铜陵市人民医院呼吸内科,安徽铜陵244000

出　　处：《安徽医药》2006年第9期655-656,共2页Anhui Medical and Pharmaceutical Journal

摘　　要：目的 探讨中心静脉导管引流联合胞必佳胸腔内注射治疗恶性胸腔积液的疗效。方法 选择恶性胸腔积液患者54例，均用中心静脉导管穿刺引流胸水，随机分为两组给药，A组25例，每次用胞必佳800μg注入胸膜腔中；B组29例，每次用顺铂80～100mg注入。最多3次。结果 A组总有效率88．0％，B组总有效率68．9％，两组疗效无显著差异（P〉0．05）。结论 胞必佳是治疗恶性胸腔积液的一种有效药物，而中心静脉导管的应用，更利于治疗的进行。Aim To evaluate the effect of central venous catheter combined with nocardia rubra cell wall skeleton （N-CWS） on treating malignant pleural effusion（MPE）. Methods 54 patients with MPE applied with central venous catheters to drain the pleural effusion were divided into two groups. For 25 cases in the group A, N-CWS 800μg was used, while 29 cases in group B, cisplation （DDP） 80-100 mg was injected. Result The response rate was 88.0% for group A ,68.9% for group B. There was no significant difference between the two groups （ P 〉 0.05 ）. Conclusion Draining the pleural effusion completely followed by intracavuty injection of N-CWS is effective in the treatment of MPE.

关 键 词：胞必佳 恶性胸腔积液 中心静脉导管 

分 类 号：R730.5[医药卫生—肿瘤]