利用生物信息数据库筛选乳腺癌CGH微阵列BAC克隆  

Screen-detection of BAC clones for array CGH in human breast cancer using bioinformatic databases

作　　者：赵佳[1] 郭华[1] 郭飞马[1] 

机构地区：[1]吉林大学基础医学院医学遗传教研室,长春130021

出　　处：《生物信息学》2006年第3期121-123,共3页Chinese Journal of Bioinformatics

基　　金：吉林省科技厅资助课题(980322)

摘　　要：利用CGAP数据库和UCSC数据库检索出乳腺癌发生、发展过程有意义的BAC克隆,然后利用CGAP数据库设计更有意义的BAC克隆。结果:获得1286条BAC克隆,可用于打印CGH微阵列,进行乳腺癌的检测。Both CGAP database and UCSC database were used to screen BAC clones candidates and BAC clones were finally designed with further CGAP database analysis.Total 1286 BAC clones were formulated and can be deposited on CGH mieroarray for breast cancer detection.

关 键 词：CGH微阵列 细菌人工染色体 乳腺癌 

分 类 号：R730[医药卫生—肿瘤] TP311.132[医药卫生—临床医学]