强迫症与伴强迫症状精神分裂症的临床研究  

A Clinic Study on Obsessive-compulsive Disorder and Schizophrenia with Obsessive-compulsive Symptoms

作　　者：陈平周[1] 陈幼然[1] 刘少文[1] 

机构地区：[1]汕头大学精神卫生中心,广东汕头515063

出　　处：《汕头大学医学院学报》2006年第3期167-168,171,共3页Journal of Shantou University Medical College

摘　　要：目的:比较强迫症与伴强迫症状的精神分裂症的临床特点。方法:采用强迫症状评定量表(Y-BOCS)、Hamilton抑郁量表(HAMD)、Hamilton焦虑量表(HAMA)、阳性症状与阴性症状量表(PANSS),对32例强迫症和38例伴强迫症状的精神分裂症进行评定分析,用氯丙咪嗪治疗并比较疗效。结果:强迫症组的Y-BOCS、HAMD、HAMA等总分明显高于伴强迫症状的精神分裂症组(P<0.01);治疗后各量表总分明显下降(P<0.01)。结论:强迫症的强迫体验、抑郁、焦虑等较明显,氯丙咪嗪疗效明显;对伴强迫症状的精神分裂症可联合用药。Objective： To compare the clinic features of obsessive-compulsive disorder and schizophrenia with obsessive-compulsive symptoms. Methods： The obsessive-compulsive disorder（32 cases）and schizophrenia with obsessive-compulsive symptoms（38 cases）were assessed by Y-BOCS, Hamilton depression rating scale for depression（HAMD）, Hamilton depression rating scale for anxiety（HAMA）, positive and negative syndrome scale（PANSS）, after treamaent with chlorimipramine. Results： The score of Y-BOCS, HAMD, HAMA in obsessive-compulsive disorder group was higher than that in schizophrenia group with obsessive-compulsive symptoms（ P 〈 0.01）. Conclusion： The obsessive-compulsive symptoms, depression, anxiety are severer in obsessive-compulsive disorder, chlorimipramine is effective and the drug combination is necessary for schizophrenia with obsessive-compulsive symptoms.

关 键 词：强迫症 精神分裂症 

分 类 号：R749.3[医药卫生—神经病学与精神病学]