磁源成像定位结节性硬化症患儿的致痫区  

Magnetic source imaging localizes epileptogenic zone in children with tuberous sclerosis complex

作　　者：Wu J. Y. Sutherling W. W. Koh S. 李青波(译) 

机构地区：[1]Division of Pediatric Neurology, Mattel Children's Hospital at UCLA, David Geflfen School of Medicine, Los Angeles, CA 90095-1752, United States [2]不详

出　　处：《世界核心医学期刊文摘（神经病学分册）》2006年第9期20-21,共2页Digest of the World Core Medical Journals:Clinical Neurology

摘　　要：The authors assessed whether magnetoencephalography/magnetic source imaging (MEG/MSI) identified epileptogenic zones in patients with tuberous sclerosis complex (TSC). In six TSC children with focal seizures, ictal video-EEG predicted the region of resection with 56%sensitivity, 80%specificity, and 77%accuracy (p = 0.02), whereas interictal MEG/MSI fared better (100%, 94%, and 95%, respectively; p < 0.0001). Interictal MEG/MSI seems to identify epileptogenic zones more accurately in children with TSC and focal intractable epilepsy.The authors assessed whether magnetoencephalography/ magnetic source imaging （MEG/MSI） identified epileptogenic zones in patients with tuberous sclerosis complex （TSC） In six TSC children with focal seizures, ictal video-EEG predicted the region of resection with 56% sensitivity, 80% specificity, and 77% accuracy （p = 0.02）, whereas interictal MEG/MSI fared better （100%, 94%, and 95%, respectively; p 〈 0. 0001） . Interictal MEG/MSI seems to identify epileptogenic zones more accurately in children with TSC and focal intractable epilepsy.

关 键 词：结节性硬化症 磁源成像 患儿 局灶性癫痫发作 病区 发作间期 癫痫发作期 顽固性癫痫 

分 类 号：R758.3[医药卫生—皮肤病学与性病学]