超声检测原发性高血压患者颈动脉粥样硬化和颅内动脉血流动力学的变化  

Detecting the changes of carotid atherosclerosis and intracranial arterial hemodynamics with ultrasonography in patients with essential hypertension

作　　者：庄丽[1] 曲延顺[1] 

机构地区：[1]新疆生产建设兵团医院功能科,乌鲁木齐830002

出　　处：《中国脑血管病杂志》2006年第9期399-402,共4页Chinese Journal of Cerebrovascular Diseases

摘　　要：目的探讨高血压病患者颈动脉粥样硬化及颅内动脉血流动力学的变化。方法选择107例原发性高血压患者,将其分为单纯高血压病组(63例)和高血压合并心、脑血管病组(44例);另外选择53名体格检查正常者为对照组。采用彩色多普勒血流显像(CDFI)及经颅多普勒超声(TCD)对患者颅内动脉及颈动脉进行检测。结果TCD颅内动脉检测结果提示,单纯高血压组和高血压合并心、脑血管病组舒张期末血流速度较对照组明显减低(P<0.01);血管搏动指数及阻力指数均高于对照组(P<0.01)。单纯高血压病组颈动脉内膜(IMT)增厚及斑块检出率分别为73.02%(46/63)和50.79%(32/63),高血压合并心脑血管病组检出率均为100%,对照组为20.75%(11/53)、19.98%(9/53),三组比较差异均有显著性,P<0.01。结论高血压是引起颅内外动脉硬化病变的重要危险因素;CDFI结合TCD可以对高血压病患者颅内、外动脉血流动力学的变化进行客观的评价。Objective To discuss the changes of carotid atherosclerosis and intracranial arterial hemodinamics in patients with essential hypertension. Methods One hundred and seven patients with essential hypertension were divided into two groups： The simple hypertension group （ n = 63） and hypertension complicated by cardio-cerebrovascular diseases group （n =44）. In addition, 53 healthy persons were selected as the control group, The pitents were detected with color Doppler flow imaging （CDFI） and transcranial Doppler uhrasonography （TCD）, and the results were analyzed retrospectively, Results The results of TCD examination of intracranial arteries suggested that the end-diastolic blood velocity in the simple hypertension group and hypertension complicated by cardio-cerebrovascular disease group were significantly lower than that in the control group （P 〈0. 01 ） ; and both the pulsitive index and vascular resistance index were higher than the control group （P 〈 0, 01 ）. The detectable rates of increased carotid intima-media thickness （IMT） and plaques in the group of simple hypertension group were 73, 02% （46/63） and 50. 79% （32/63） ; the detectable rates of increased IMT and plaques in the hypertension complicated by cardio-cerebrovascular disease group were all 100% , and they were significantly higher than those in the control group [20.75% （11/53） and 19.98% （9/53; P〈0.01）]. Conclusion Essential hypertension is an important risk factor for intracranial arteriosclerosis, CDFI combined with TCD may objectively evaluate the changes of hemodinamics of intracranial and extracranial arteries in patients with essential hypertension.

关 键 词：高血压 颈动脉疾病 超声检查 多普勒 血液动力学 

分 类 号：R743[医药卫生—神经病学与精神病学] R445.1[医药卫生—临床医学]