基底节病变时语言障碍的书写特点  

The writing characteristics of language disorder in patients with basal ganglia lesions

作　　者：刘晓加[1] 戴蓉[1] 邵明[2] 吴卓华[2] 金梅[1] 谢秋幼[1] 尹文刚[3] 

机构地区：[1]南方医科大学南方医院神经内科,广州510515 [2]广州医学院第一附属医院神经内科 [3]中国科学院心理研究所

出　　处：《中国神经精神疾病杂志》2006年第5期418-422,共5页Chinese Journal of Nervous and Mental Diseases

基　　金：国家自然科学基金课题(编号:39870268;30370486)

摘　　要：目的通过对基底节病变时患者语言障碍及汉字书写特点的研究,探讨其可能的神经心理学机制。方法对103例基底神经节病变患者采用汉语失语检查法(ABC法)和汉语失写检查法(CAB法),从听、说、读、写4个方面全面评估患者的语言能力,筛选出语言障碍者40例,确定其书写障碍的类型、严重程度及其与其他语言障碍之间的相关性。结果除书面理解和口语表达间差异无显著性意义外,其余口语和书面语语言障碍间的差异均有显著性意义。在口语表达与书面语表达各项之间均存在正相关关系,在书面语理解与书面语表达之间均存在正相关关系,基底节病变书写障碍程度左侧重于右侧,双侧最轻。结论在基底神经节病变的口语和书面语损害之间,既相互联系又各具特点,基底神经节参与言语和书写过程的神经心理学机制是有所差异的。Objective To study the feature of speech and Chinese character on basal ganglia language disorder, and approach the possible mechanism of neuropsychology. Methods In 103 basal ganglia damaged patients, ABC and CAB were used to examine the ability of hearing, speaking, reading and writing, appraise overall language damage degree. Forty patients with language disorder were selected to determine agraphia type and degree, relationship with other language disorders. Result Except for no significant difference between written apprehension and spoken language expression, there were significant difference in other language disorders between written language and spoken language. There was positive correlation between spoken language expression and written language expression in each aspect. There was positive correla- tion between written language apprehension and written language expression. In basal ganglia language disorder, written dis- order was severer in left side than right side, ganglia damaged in both sides had the least written disorder. Conclusion In damaged basal ganglia, there exist both correlation and difference between spoken language and written language. The mechanism of neuropsychology is different that basal ganglia participate in the process of speech and writing.

关 键 词：基底神经节 书写障碍 神经心理学 

分 类 号：R743.3[医药卫生—神经病学与精神病学]