矢量分析后的角膜散光与眼二阶波阵面像差的相关性研究  

The relationship between corneal astigmatism with a Vector-based method and whole eye second order wavefront aberrations

作　　者：吴江秀[1] 吕帆[1] 贺极苍[2] 胡亮[1] 沈烨宇[1] 陈世豪[1] 许琛琛[1] 瞿佳[1] 

机构地区：[1]温州医学院眼视光学院,325027 [2]美国新英格兰视光学院

出　　处：《中华眼科杂志》2006年第9期782-787,共6页Chinese Journal of Ophthalmology

基　　金：十五国家科技攻关计划资助项目(2004BA720A16)

摘　　要：目的了解国人近视眼患者中角膜散光与眼二阶波阵面像差的关系以及角膜散光在眼像差组成中的影响和作用。方法使用 Shack-Hartmann 原理设计的 WASCA 波阵面像差分析仪检测246例门诊患者484只近视散光眼的眼像差,6.0mm 瞳孔直径下,以第三、五项 Zernike 系数(C_3和C_5)进行分析;使用 Humphrey 角膜地形图对484只眼进行检测,获得角膜散光度数,分为顺规(包括0°与180°两类)、逆规、斜轴(包括45°与135°两类)5组角膜散光,各自矢量分解为 J_(45)(轴在45°或135°的 JCC 柱镜)与 J_0(轴在90°或180°的 JCC 柱镜)后分别与第二阶像差进行相关分析。结果由矢量分析所得的各组角膜散光平均值分别为-1.34D×6.87°、-1.03D×23.15°、-0.48D×89.55°、-0.91D×156.87°、-1.02D×176.74°;各组角膜散光的 J_(45)和 J_0值分别与 C_3和 C_5呈线性相关,其中 J_(45)与 C_3的线性回归公式确定系数 R^2依次为0.138、0.119、0.090、0.526、0.501;J_0与 C_5的确定系数 R^2依次为0.711、0.736、0.864、0.866、0.785。结论角膜散光与眼二阶波阵面像差关系密切,两者的相关呈散光轴向依赖性。角膜散光与眼内散光的不同互补和叠加模式随散光轴向的变化而规律变化。Objective To investigate the relationship between corneal astigmatism and second order wavefront aberration in myopic eyes. Methods The corneal astigmatism and the whole eye wavefront aberrations of both eyes of 246 subjects were measured using the Humphrey corneal topography and the WASCA wavefront analyzer. According to axial of the corneal astigmatism, the subjects were divided into five groups （WR0, WR180, AR, OA45 and OA135 ）. The corneal astigmatism was decomposed into J45 and J0 with a Vector-based method, and correlated with the 2nd order Zernike aberrations （ C3 and C5 ）. Results The mean corneal astigmatisms for the five groups were -1.34D×6.87°、-1.03D×23.15°、-0.48D×89.55°、-0.91D×156.87°and -1.02D×176.74° respectively. Most of the corneal J45 and J0 components were correlated significantly with the C3 and the C5 aberrations in the whole eye. While the correlation coefficients （R^2 ） between the J45 and the C3 were 0. 138, 0.119, 0.090, 0.526 and 0. 501, the R^2 between the J0 and the C5 were 0. 711,0. 736, 0.864, 0. 866 and 0.785 for the five groups respectively. Conclusions The corneal astigmatism plays an important role in determining the 2nd order wavefront aberration in the whole eye, and the combination processes between the corneal and internal astigmatism （compensation and/or addition ） change with the axial of the corneal astigmatism.

关 键 词：近视 角膜散光 像差 屈光 眼 

分 类 号：R778.11[医药卫生—眼科]