酪蛋白酶解物对宫内生长迟缓新生仔猪小肠生长发育的影响  

Effects of casein hydrolysate on the intestinal growth and development in intrauterine growth retardation neonatal piglets

作　　者：沈峰[1] 张莉莉[1] 霍永久[1] 林桂娟[1] 王恬[1] 

机构地区：[1]南京农业大学动物科技学院,江苏南京210095

出　　处：《南京农业大学学报》2006年第3期59-63,共5页Journal of Nanjing Agricultural University

基　　金：国家自然科学基金资助项目(30471253)

摘　　要：为探讨酪蛋白酶解物对宫内生长迟缓仔猪小肠生长发育的影响,选择胎儿在母体内发育迟缓(IUGR)初生仔猪15头,分为新生对照组(N)、酪蛋白组(C)和酪蛋白酶解物组(CH),以牛乳为基础日粮,C组用1.5%酪蛋白溶液取代10%(体积分数)的牛乳,CH组用1.5%酪蛋白酶解液取代10%(体积分数)的牛乳,人工饲喂3 d后宰杀取样。结果表明:CH组仔猪小肠黏膜DNA含量及麦芽糖酶活性较N组显著提高(P<0.05),而C组与N组相比未发生显著变化(P>0.05)。此外,与N组仔猪相比,C组仔猪小肠各段绒毛高度都有不同程度降低(P>0.05),而CH组仔猪小肠各段绒毛高度与N组仔猪接近,未有明显变化。提示:酪蛋白酶解物有刺激新生IUGR仔猪小肠黏膜上皮细胞的增殖和提高麦芽糖酶活性的趋势。The effects of casein hydrolysate on the growth and development of small intestine in intrauterine growth retardation （ IU- GR） piglets were examined in this study. Fifteen piglets were selected and divided into newborn control group （ N）, casein group （C） and casein hydrolysate group （CH）. The cow-milk was taken as the basic feed, piglets in groups C and CH were fed milk substituted 1.5% casein and 1.5% casein hydrolysate solution for 10% milk, respectively. The piglets were slaughtered and sampled after feeding 3 days. The results indicated that the contents of DNA and the total activity of maltase of small intestine mucosa in groups CH were significantly increased than those in group N （ P 〈 0. 05 ）, but no changes were found between group N and group C （P 〉 0. 05 ）. In addition, the villus height of small intestine in group C was decreased than that in group N, but no changes were found between group N and group CH （P 〉 0. 05）. In conclusion, the casein hydrolysate showed tendency to stimulate the proliferation of the epithelium cell and increased the total activity of maltase in newborn IUGR piglets.

关 键 词：宫内发育迟缓 酪蛋白酶解物 小肠 消化酶 新生仔猪 

分 类 号：S858.28[农业科学—临床兽医学]