应用全身^(18)F-FDG PET/PET-CT为脑转移瘤患者寻找原发灶  

Detection of the Primary Tumor in Brain Metastasis by Whole Body ^(18)F-FDG PET/PET-CT

作　　者：王欣璐[1] 王全师[1] 吴湖炳[1] 王巧愚[1] 李洪生[1] 

机构地区：[1]南方医科大学附属南方医院PET中心,广东广州510515

出　　处：《实用放射学杂志》2006年第9期1130-1133,共4页Journal of Practical Radiology

基　　金：2003年度国家自然科学基金资助项目(No:30370426);2005年度国家自然科学基金资助项目(No:30500136)。

摘　　要：目的评价全身18F-FDG PET/PET-CT在脑转移瘤寻找原发灶中的诊断价值。方法对67例以脑转移瘤查找原发灶为主诉的肿瘤患者的18F-FDGPET/PET-CT资料进行回顾性分析。结果本组67例患者中57例患者的原发灶位置得到了确诊,原发灶的检出率为85.1%;其中原发性肺癌29例,占50.9%;所有肺癌中病理分型为低分化腺癌者共13/29例,占44.8%。除可检出原发灶外,18F-FDG PET/PET-CT全身显像还检出肺转移、淋巴结转移、骨转移、肝转移及其他少见部位的转移灶。与18F-FDGPET-CT相比,单纯的18F-FDGPET图像对肺转移病灶的检出率仅为10.9%。结论18F-FDGPET/PET-CT的全身扫描有利于发现原发灶及其他转移灶。Objective To evaluate the value of whole body ^18F - FDG PET/PET - CT in detection of the primary tumor in brain metastasis. Methods ^18F - FDG PET/PET - CT in 67 patients with initial complain of multiple metastatic tumors in the brain were analysed retro- spectively. Results Of 67 patients, the position of primary tumors was determined by whole body ^18F - FDG PET/PET - CT in 57 cases, the detecting rate was 85.1%. Of them,29 cases were primary pulmonary cancer（ 50.9% ） ,among them, 13 cases were the poor differentiation adenocarcinoma（ 44.8% ）. Additionally the metastasis in bone,lung and liver were detected stimultaneously,and some rare metastases in the other part of whole body were determined either. In comparison to ^18F - FDG PET - CT,the sensitivity for detection of lung metastasis by ^18F - FDG PET was only 10.9%. Conclusion The whole body scan of ^18F - FDG PET/PET - CT is benefit for finding out the primary tumors and metastasis,

关 键 词：脑 转移瘤 原发灶 正电子发射计算机体层摄影 

分 类 号：R739.41[医药卫生—肿瘤] R814.42[医药卫生—临床医学]