冰黄五苓散喷雾干燥工艺研究  

Study on Process for the Spray Drying of BINGHUANGWULING Pulveres

作　　者：郑国燊[1] 余尚贞[1] 石青[1] 艾立新[1] 

机构地区：[1]暨南大学医学院第六附属医院/广东省江门市五邑中医院,广东江门529031

出　　处：《中国实验方剂学杂志》2006年第9期1-2,共2页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：广东省中医药管理局资助课题(NO:102126)

摘　　要：目的选择冰黄五苓散喷雾干燥的最佳工艺条件。方法应用正交试验法,以每小时药粉产量、含水量为考察指标,对影响冰黄五苓散喷雾干燥过程的塔前风温、风压和浸膏相对密度等三因素进行考察。结果正交试验法设计的三个因素中,考察收粉量,浸膏的相对密度影响较显著,入塔风压和塔前风温影响不显著;考察含水量,浸膏的相对密度、入塔风压和塔前风温的影响均不显著。结论最佳工艺条件为入塔风温180℃,入塔风压-1500Pa,浸膏相对密度为1·22;采用喷雾干燥工艺生产的冰黄五苓散有效成分中大黄素的含量和水浸出物明显高于原冰黄五苓液。Objective： To selects the optimum conditions for the spraydrying of BINGHUANGWULING Pulveres. Methods： The process was studieds by orthogonal experimental design with the average output of the extract powder and water percent as the detective marker about the relative density of the extractive, the blast pressure and the wind temperature. Results： The relative density of the extractive is table effect and the other conditions are notable effect. Conclusion： It＇s the optimum process： The wind temperature is 180℃, The blast pressure is - 1500Pa, The relative demsity is 1.22; the content of emodin in the BINGHUANGWULING Pulveres manufactured by the process of the spaydrying was higher than the BINGHUANGWULING Mixture.

关 键 词：冰黄五苓散 喷雾干燥 脑出血 出粉量 含水量 

分 类 号：R283.6[医药卫生—中药学]