肝硬化患者血清微量元素的检测及其临床意义  

Serum levels of trace elements and its clinical significance in patients with liver cirrhosis

作　　者：王翠兰[1] 周仁[1] 景元海[1] 那连涛[2] 石益海[2] 李宏伟[2] 董秉洲[2] 

机构地区：[1]大庆龙南医院,黑龙江大庆163453 [2]大庆油田总医院,黑龙江大庆163001

出　　处：《中国实验诊断学》2006年第8期883-885,共3页Chinese Journal of Laboratory Diagnosis

摘　　要：目的探讨肝硬化患者血清微量元素水平与病情的相关性。方法采用日立7170A全自动生化分析仪检测肝硬化90例及40例正常对照者血清中镁、铁、铜、锌的水平。结果肝硬化患者血清镁、锌水平均显著低于正常对照组(P<0.01),血清中镁、锌水平以ChildPughC级组最低。肝硬化患者血清铜、铁水平均显著高于正常对照(P<0.01),以ChildPughC级组最高。结论检测肝硬化患者血清中的微量元素,对了解病情及指导临床治疗具有一定的意义。Objective To investigate the relationship between serum levels of trace elements and severity in patients with liver cirrhosis.Methods Serum levels of magnesium,iron,copper and zinc were determined by Hitachi 7170A TM biochemical analysator in 90 patients with liver cirrhosis,and 40 normal subjects.Results Compared with the controls,magnesium and zinc levels decreased and copper and iron contents increased in liver cirrhosis （ P 〈 0. 01 ）, especially in Child-Pugh C. Conclusion Serum microelement detection in patients with hver cirrhosis is helpful in the severity judgment and regimen design.

关 键 词：肝硬化 微量元素 血清 

分 类 号：R575.2[医药卫生—消化系统]