^(18)F-FDG PET对乳腺癌复发和转移的诊断价值  

Diagnostic value of ^(18)F-FDG PET in recurrent and metastatic breast cancer:a Meta analysis

作　　者：郭兴[1] 李林[1] 彭伟凯[1] 沈绍群[1] 赵祯[1] 

机构地区：[1]四川大学华西医院核医学科,成都610041

出　　处：《中华核医学杂志》2006年第4期201-204,共4页Chinese Journal of Nuclear Medicine

摘　　要：目的汇总分析^(18)F-脱氧葡萄糖(FDG)PET 诊断乳腺癌复发和转移的文献,评价其诊断效能。方法检索1995年1月～2005年8月 Medline、循证医学数据库(EBMR)、中国生物医学文献数据库光盘版(CBMdisc)中的中文和英文文献,对纳入文献进行质量评价,异质性检验,用统计分析软件计算综合受试者工作特征(SROC)曲线方程,绘制 SROC 曲线,得到灵敏度、特异性和综合优势比。结果 14篇文献被纳入,进行 SROC 分析,综合灵敏度和特异性分别为88.6%和85.6%.综合优势比为60.3。结论 ^(18)F-FDG PET 对乳腺癌复发和转移有诊断价值。Objective To assess overall diagnostic value of ^18F-fluorodeoxyglucose （FDG） PET in patients of recurrent and metastatic breast cancer with Meta analysis. Methods Search in Medline, Evidence-Based-Medicine Review （EBMR） and Chinese-Biomedicine disc （CBMdisc） was performed to identify relevant articles in English and Chinese from January 1995 to January 2005 . After evaluating all articles that had been elicited, the pooled sensitivity, specificity and odds rate were calculated by using summary receiver operating characteristic （SROC） curve. Results Fourteen articles that had been elicited were included in this Meta analysis. The pooled sensitivity, specificity and odds rate were 88.6% , 85.6% and 60.3 respectively. Conclusion ^18F-FDG PET is a valuable tool for detecting recurrent and metastatic breast cancer.

关 键 词：乳腺肿瘤 体层摄影术 发射型计算机 肿瘤复发 局部 肿瘤转移 脱氧葡萄糖 文献工作 

分 类 号：R737.9[医药卫生—肿瘤]