乳腺癌术后胸壁电子线放射治疗的剂量分布  

Dose distribution of chest wall electron beam radiotherapy for patients with breast cancer after radical mastectomy

作　　者：丛也彤[1] 陈大伟[1] 白岚[1] 周银行[2] 朴永峰[3] 王溪[3] 曲雅勤[3] 

机构地区：[1]吉林大学公共卫生学院辐射防护教研室 [2]吉林大学物理学院核物理教研室,吉林长春130023 [3]吉林大学第二医院放疗科,吉林长春130041

出　　处：《吉林大学学报（医学版）》2006年第5期832-834,共3页Journal of Jilin University：Medicine Edition

基　　金：中国卫生部国家标准资助项目(2002)

摘　　要：目的:对乳腺癌术后胸壁放射治疗时不同能量电子线照射不同厚度组织等效膜产生的剂量进行测量及分析。方法:以射线选用6及9MeV电子束的电子直线加速器对仿真人体组织等效模型所拟的典型成年女子左侧乳腺癌术后患者进行模拟照射,用热释光剂量仪进行实际测量。结果:在无膜及体表加盖0·5及1·0cm组织等效膜后,6MeV电子线照射时皮肤表面的剂量提高,分别为184·7,217·8和220·4cGy,肺受照剂量减少,分别为63·7,30·7和13·4Cgy;9MeV电子线照射时皮肤表面的剂量提高,分别为163·8、170·7和191·5cGy,肺受照剂量减少,分别为173·9、101·7和86·9cGy。结论:不同能量电子线照射时,在体表加盖0·5及1·0cm厚的组织等效膜后,皮肤表面剂量提高,肺前缘受照剂量减少,电子线能量增加,高剂量坪区加宽;电子线能量相同时随着等效膜厚度的增加,高剂量坪区向表皮移动;可以通过增加一定厚度的等效膜来提高整个靶区治疗的剂量要求。Objective To study the dose distribution of different bolus after different energy electron beam irradiation to different chest wall radiotherapy for the patients with breast cancer. Methods The paper simulated the dose distribution of women＇s left breast cancer after radical mastectomy by 6 and 9MeV electron beam irradiation, and TLD was used to measure. Results The dose of skin became higher and the dose of lung was less when 0.5 and 1.0 cm bolus were used on the body; with the increasing of the energy of electron beam, the high dose field became larger; and with the same energy of electron beam, the high dose field moved to surface of the body when the bolus was thicker. Conclusion When different energy electron ray irradiates different thickness bolus , the dosage of skin surface increases and the dosage of anterior margin of lung reduces. With electron ray energy increasing , the high dosage field is widen , when the electron ray energy is identity , the high dosage field migrates to the surface after adding bolus. Using certain depth bolus may attain the therapeutical dose of target area.

关 键 词：乳腺肿瘤 放射疗法 辐射剂量 高剂量坪区 

分 类 号：R737.9[医药卫生—肿瘤] R730.55[医药卫生—临床医学]