VCE取材Bethesda 2001报告在宫颈癌筛查中的意义  

Significance of VCE smear and Bethesda 2001 report system in screening of cervical carcinoma

作　　者：韩淑梅[1] 张晓霞[1] 冯丽华[1] 王桂如[2] 李艺扬[1] 金今玉[3] 

机构地区：[1]吉林大学第一医院妇产科,吉林长春130021 [2]吉林大学第一医院干部病房,吉林长春130021 [3]吉林省龙井市人民医院妇产科

出　　处：《吉林大学学报（医学版）》2006年第5期906-909,共4页Journal of Jilin University：Medicine Edition

基　　金：吉林省科技厅基金资助课题(20030538-5)

摘　　要：目的:探讨VCE取材Bethesda2001报告系统在宫颈癌筛查中的意义。方法:采用VCE取材Bethesda2001报告系统对3056例健康体检女性进行阴道细胞学检查,并对不明确意义的不典型鳞状上皮细胞(ASC-US)以上病变者经阴道镜取材进行宫颈组织病理学诊断。结果:阴道细胞学检查(VCE取材Bethesda2001报告系统)检出宫颈异常鳞状上皮细胞66例,阳性率2·15%。其中不明确意义的不典型鳞状上皮细胞(ASC-US)17例(25·76%),不除外高度病变的不典型鳞状上皮细胞(ASC-H)4例,(6·06%),低度鳞状上皮内病变(LSIL)28例(42·42%),高度鳞状上皮内病变(HSIL)14例(21·21%),宫颈鳞癌(SCC)3例(4·55%)。66例细胞学阳性诊断病例经宫颈活检组织病理学诊断CINI级以上病变60例(90·91%),其中CINⅠ级35例(53·03%),CINⅡ级12例(18·18%),CINⅢ级7例(10·61%),宫颈鳞癌6例(9·09%)。结论:VCE取材Bethesda2001报告系统取材方便、报告准确,阴道细胞学检查阳性诊断与病理诊断符合率高达90·91%,VCE取材Bethesda2001报告系统在宫颈癌筛查中具有重要意义。Objective To discuss the significance of VCE smear and the Bethesda 2001 report system in screening of cervical carcinoma. Methods 3 056 healthy examination population were examined for cervical-vaginal cytology by VCE smear and the Bethesda 2001 report system. All of the cases were biopsied by coloscopy including atypical squamous cells of undetermined significance （ASC-US）, squamous intraepithelial lesions and carcinoma （SIL＋）. Results 66 cases of SIL ＋ were found in cervical-vaginal cytology （2.15%）, including 17 cases of atypical squamous cells with undetermined significance （ASC-US） （25.76%）, 4 cases of atypical squamous cells, didn＇t exclude HSIL （ASCH） （6.06%）, 28 cases of low grade SIL （LSIL） （42.42%）, 14 cases of high-grade SIL （HSIL） （21.21%）, 3 cases of squamous cervical carcinoma （SCC） （4.55%）. In 66 cases of cervical-vaginal cytology positive results, 60 cases of CIN Ⅰ＋ were confirmed by biopsy pathology, including 35 cases of CIN Ⅰ （53.03%）, 12 cases of CIN Ⅱ （18.18%）, 7 cases of CIN Ⅲ （10.61%）. Conclusion VCE smear and the Bethesda 2001 report system can get cells conveniently and the results are more correct. The coincidence of the examination of cervical-vaginal cytology and pathology is 90.91 %. VCE smear and the Bethesda 2001 report system has great significance in screening of cervical carcinoma.

关 键 词：VCE取材 Bethesda2001报告 体格检查 宫颈疾病/诊断 宫颈肿瘤 普查 

分 类 号：R730.43[医药卫生—肿瘤] R737.33[医药卫生—临床医学]