颈淋巴结活检对鼻咽癌预后的影响  

The influence of cervical lymph node biopsy of nasopharyngeal cancer(NPC) on prognosis

作　　者：何林[1] 何报宁[1] 陈松[1] 

机构地区：[1]广西玉林市第二人民医院肿瘤科,广西玉林537000

出　　处：《现代肿瘤医学》2006年第10期1208-1209,共2页Journal of Modern Oncology

摘　　要：目的:探讨颈淋巴结活检对鼻咽癌预后的影响。方法:收集、确诊治疗前行颈淋巴结活检的鼻咽癌58例和同期仅行鼻咽部活检的鼻咽癌60例。分析两组远处转移率、5年生存率以及颈淋巴结活检后距专科治疗时间与远处转移率、5年生存率的关系。结果:鼻咽部活检组与颈淋巴结活检组远处转移率为20%(12/60)与39.66%(23/58)(P<0.05),两组5年生存率为50%(30/60)与29.31%(17/58)(P<0.05)。颈淋巴结活检后2周内和2周后行专科治疗远处转移率为26.67%(8/30)和53.57%(15/28)(P<0.05);两组5年生存率为40%(12/30)与21.43%(6/28)(P>0.05)。结论:鼻咽癌颈淋巴结活检及术后未及时行专科治疗影响鼻咽癌患者的预后。Objective ：To determine the influence of cervical lymph node biopsy of nasopharyngeal cancer（NPC） on prognosis. Methods： To collect 58 cases with NPC who have finished cervical lymph node biopsy and 60 cases just nasopharyngeal biopsy before treatment and diagnoses. Distant metastasis and survival rate in 5 years were ana- lyzed in two groups. Compared the relation of time from cervical lymph node biopsy to special therapy and distant metastasis and survival rate in 5 years in group with cervical lymph node biopsy. Results： Distant metastasis rates in group of cervical lymph node biopsy and group nasopharyngeal biopsy were 20% （12/60） and 39.66% （23/58） ; survival rate in 5 years 50% （ 30/60 ）, 29.31% （ 17/58 ） respectively （ P 〈 0.05 ）. Patients were treated with special treatment in two weeks and after two weeks in group of cervical lymph node biopsy, the distant metastasis rates were 26.67 % （ 8/30 ） and 53.57 % （ 15/28 ） respectively （ P 〈 0.05 ） ; survival rates in 5 years 40% （ 12/30）, 21.43 % （6/ 28 ）respectively （P 〉 0.05 ）. Conclusion： The prognosis of patients with NPC will be influenced if they were not performed cervical lymph node biopsy.

关 键 词：鼻咽肿瘤 放射治疗 化学治疗 颈淋巴结活检 

分 类 号：R739.6[医药卫生—肿瘤]