胃癌高发区功能性消化不良与萎缩性胃炎幽门螺杆菌感染分析  

The relationship between functional dyspepsia and chronic atrophy gastritis with Helicobacter Pylori infection in the area with high gastric cancer incidence

作　　者：魏晓萍[1] 惠起源[1] 冯义朝[1] 党冬梅[1] 崔轶霞[1] 张小用[1] 

机构地区：[1]延安大学医学院,陕西延安716000

出　　处：《现代肿瘤医学》2006年第10期1259-1260,共2页Journal of Modern Oncology

基　　金：陕西省教育厅自然科学专项(05JK316)

摘　　要：目的:探讨胃癌高发区功能性消化不良(FD)与萎缩性胃炎(CAG)幽门螺杆菌(Hp)感染率及与胃癌高发的关系。方法:经过确诊的78例FD病例和69例CAG病例作为研究对象,通过病理组织学Giemsa染色法确定其Hp感染情况。结果:FD患者的HP感染率为42.3%(33/78),CAG患者的Hp感染率为72.5%(50/69),两组差异有显著性(P<0.01)。结论:该地区的CAG患者Hp感染率高于FD患者的Hp感染率;在该胃癌高发区,CAG的Hp感染率较高,胃癌高发病率可能与Hp感染率高有关。Objective ：To explore the correlation between Helicobacter pylori （Hp） infection rate and functional dyspepsia and chronic atrophy gastritis, and the relationship between Hp infection rate with the high gastric cancer incidence. Methods ： Seventy eight cases of FD and 69 cases of CAG were studied through histopathology Giemsa staining method to detect Hp infection. Results： Hp infection rate of FD was 42.3 % （33/78）, in CAG 72.5 % （50/69） （P 〈0.01 ）. Conclusion： Hp infection rate in CAG is higher than that in FD in this area with the high gastric cancer incidence ;high incidence of gastric cancer maybe related with Hp infection.

关 键 词：胃癌高发区 功能性消化不良 萎缩性胃炎 幽门螺杆菌 

分 类 号：R735.2[医药卫生—肿瘤]