Tono-Pen眼压计对兔眼不同部位眼压测量值的相关性研究  

Correlation analysis of intraocular pressure obtained from different points in rabbit's eyeball with Tono-Pen tonometer

作　　者：张虹[1] 李贵刚[1] 胡军[1] 胡维琨[1] 孙旭芳[1] 赵春明[1] 

机构地区：[1]华中科技大学同济医学院附属同济医院眼科,湖北省武汉市430030

出　　处：《眼科新进展》2006年第10期744-746,共3页Recent Advances in Ophthalmology

摘　　要：目的研究兔眼球不同部位测量眼压(intraocular pressure,IOP)值的相关性规律。方法采用Tono-Pen眼压计全身麻醉下测量40只新西兰白兔角膜中央、旁中央区、角膜缘及巩膜部位IOP值,同时采用Schiotz眼压计测量角膜中央IOP值。采用SPSS软件分析不同部位IOP测量值间的相关性。结果兔角膜中央区、旁中央区、角膜缘及角膜缘后4mm巩膜部位IOP值分别为(19.44±2.33)mmHg(1kPa=7.5mmHg)、(19.44±1.95)mmHg、(21.66±4.26)mmHg和(21.83±4.84)mmHg,Schiotz眼压计测量角膜中央IOP值(19.27±3.14)mmHg。角膜旁中央区与角膜中央区IOP值有相关性,检验有统计学意义(R=0.615,P=0.007<0.01),而角膜缘、角膜缘后4mm巩膜与角膜中央区IOP值相关系数及P值分别为0.537/0.021、0.215/0.391。结论采用Tono-Pen眼压计测量兔眼角膜旁中央区或角膜缘眼压可以反映眼压实际值。Objective To study the correlation of the intraocular pressure （IOP） obtained from different points in rabbit＇s eyeball. Methods The IOP of forty New Zerland white rabbits（eighty eyes） were examined by Tono-Pen tonometer under general anesthesia at central cornea, pericentral cornea, lirabus and sclera （four millimeter behind the corneal limbus）, and schiotz tonometer was used to measure the IOP at central cornea. The correlative rates of IOP obtained from different points were analyzed with SPSS software. Resuits The IOP obtained from central cornea, pericentral cornea, limbus and sclera by Tono-Pen tonometer were （ 19.44± 2.33） mmHg （ 1 kPa= 7.5 mmHg）, （19.44 ± 1.95） mmHg, （21.66 ± 4.26） mmHg and （21.83 ± 4.84） mmHg respectively,and IOP obtained from central cornea by schiotz tonometer was （19.27 ± 3.14） mmHg. There was correlation between the IOP obtained from pericentral cornea and central cornea（ R= 0. 615, P = 0. 007 〈 0.01 ） ; While the correlative rate of IOP obtained from limbus and central cornea was 0. 537（P = 0. 021 ） ,and which from sclera and central cornea was 0. 215 （P =0. 391 ）. Conclusion The IOP obtained from pericentral cornea and corneal limbus may reflect the real IOP of rabbit.

关 键 词：TONO-PEN眼压计 眼压 兔 

分 类 号：R775.1[医药卫生—眼科]