某院围手术期患者抗菌药物应用情况分析  

Analysis on Application of Antimicrobial Agents in Perioperative Patients

作　　者：方英立[1] 赵丽霞[1] 周文[1] 

机构地区：[1]山东大学齐鲁医院药学部,济南市250012

出　　处：《中国药房》2006年第19期1484-1486,共3页China Pharmacy

摘　　要：目的了解某医院围手术期患者抗菌药物应用情况,促进临床合理用药。方法依据《应用抗菌药物防治外科感染的指导意见》及《抗菌药物临床应用指导原则》,对某院随机抽取的262例围手术期患者抗菌药物应用进行回顾性分析研究。结果262例围手术期患者100%应用抗菌药物;联合应用2种抗菌药物者69%;用法、用量不合理者30%;用药时机不合理者61%;用药疗程不合理者41%;药物选择起点过高者27%;无指征联合用药者34%;手术部位感染率4.6%。感染患者中43%未作微生物培养及药敏试验,4%未根据药敏结果适当调整抗菌药物品种。结论该院围手术期患者不合理应用抗菌药物现象比较普遍、严重,许多问题亟待解决。OBJECTIVE： To analyze the application of antimicrobial agents in perioperative patients in a hospital so as to promote their rational use in the clinic.METHODS： The application of antimicrobials in 262 perioperative patients randomly selected from a hospital was reviewed retrospectively based on the Guidance on the Application of Antimicrobials .lot the Prevention of Surgical Injection and the Clinical Application Guideline on the Antimicrobials . RESULTS：Of the 262 cases, 100% received antimicrobial agents, 69% received combination of 2 drugs, 30% were irrational in usage and dosage, 61% were irrational in medication time,41% were irrational in medication duration,27% involved high starting point of drug application, 34% received drug combination yet without any indication, 4.6% involved infection of operative sites. Of those who were subjected to infection, 43% received neither microbiological culture nor susceptibility test ,and 4% didn＇t adjust the categories of antibiotics accordingly based on the results of susceptibility test.CONCLUSIONS：The phenomenon of irrational use of drugs in perioperativc patients of this hospital is widespread and serious,and there are many problems needed to be tackled urgently.

关 键 词：围手术期 抗菌药物 合理用药 

分 类 号：R978.1[医药卫生—药品]