早期原发性开角型青光眼彩色图形视网膜电图的特征  

Thefeaturesofcolorpaternelectroretinograminearlyprimaryopen┐angleglaucoma

作　　者：杨桦[1,2] 蒋幼芹[1,2] 吴振中[1,2] 

机构地区：[1]湖南医科大学附属第二医院眼科 [2]华西医科大学附属第一医院眼科

出　　处：《中华眼科杂志》1996年第4期272-276,共5页Chinese Journal of Ophthalmology

摘　　要：目的观察早期原发性开角型青光眼（ｐｒｉｍａｒｙｏｐｅｎａｎｇｌｅｇｌａｕｃｏｍａ，ＰＯＡＧ）彩色图形视网膜电图（ｃｏｌｏｒｐａｔｔｅｒｎｅｌｅｃｔｒｏｒｅｔｉｎｏｇｒａｍ，ＣＰ－ＥＲＧ）的改变特征。方法对２９例（４８只眼）ＰＯＡＧ，１０例（１６只眼）高眼压症及３３例（４８只眼）年龄匹配的正常人做ＣＰ－ＥＲＧ检测，并进行统计学比较及多因素分析。结果早期ＰＯＡＧ的ＣＰ－ＥＲＧ的Ｐ１、Ｎ２波幅下降，红黑Ｎ２与蓝黑Ｐ１峰时间延长；部分高眼压症已出现Ｎ２波幅下降。采用多因素逐步判别分析方法，筛选出对早期ＰＯＡＧ诊断有判别能力的５项指标：蓝黑Ｎ２波幅、红黑Ｐ１波幅、红黑Ｎ２波幅、红黑Ｎ２峰时间及白黑Ｐ１波幅与Ｎ２波幅的比值，同时建立了判别函数。结论ＣＰ－ＥＲＧ是检测早期ＰＯＡＧ视网膜功能改变的有效方法，有助于早期ＰＯＡＧ的诊断。ObjectiveToobservethefeaturesofthechangesofcolorpatternelectroretinogram(CP-ERG)inearlyprimaryopen-angleglaucoma(POAG).MethodThedetectionandanalysesofCP-ERGsin29patients(48eyes)withPOAG,10patients(16eyes)withocularhypertensionand33age-matchednormalvolunteers(48eyes)weremade.ResultsTheChangesofCP-ERGinearlyPOAGincludedreductionofamplitudesofP1andN2waves,prolongationofthepeaktimesofred/blackN2andblue/blackP1waves.PartofthepatientswithocularhypertensionhadtheamplitudeofN2wavereduced.Fivefactorsincludingtheamplitudeofblue/blackN2wave,theamplitudesofred/blackP1andN2waves,thepeaktimeofred/blackN2waveandthewhite/blackP1toN2waveampli-tuderatiofromCP-ERGwhicharesignificantlycorelatedtothediagnosisofearlyPOAGwerese-lectedbythemultiplefactorstepwisediscriminatoryanalysis,andthestepwisediscriminatoryfunc-tionwassetup.ConclusionsCP-ERGisausefulmethodindetectingtheretinalfunctionsinearlyPOAG,andishelpfultoitsearlydiagnosis.

关 键 词：青光眼 开角型 高眼压症 视网膜电图 

分 类 号：R775.204[医药卫生—眼科]