环氧改性与戊二醛处理的牦牛心包的扫描电镜形态比较  

A Morphological Comparison of Epoxide-treated and Glutaraldehydetreated Yak Pericardium under Scan Electron Microscope

作　　者：刘侠[1] 乐以伦[1] 黄嘉 石应康 程述森 安琪 

机构地区：[1]四川联合大学生物材料及生物技术研究所,华西医科大学附一院

出　　处：《生物医学工程学杂志》1996年第3期200-203,共4页Journal of Biomedical Engineering

摘　　要：作者将环氧改性与戊二醇固定的牦牛心包缝制成血管，然后缝合在成年家犬颈动脉上．４个月后，取出材料，作扫描电镜观察，比较两者的形态学变化，并将未被植人的牦牛心包作同步电镜观察．结果表明，环氧改性的牦牛心包更为完整，其浆膜层脱落程度小，更为光滑，胶原纤维的走向更富弹性和抗张强度。植入体内后，环氧改性的牦牛心包撕裂程度明显较低．说明环氧改性的牦牛心包的力学性能明显优于戊二醛固定的牦牛心包，材料的力学性能是由胶原纤维的走向决定的。Epoxide-treatd and glutaraldehyde-treated yak pericardia were sewn into tube and implanted intothe carotid arteries of dog. After four months, the materials were taken out and observed under scan electron microscope. Not implanted materials were observed at the same time. The result reveals that the structure of epoxide-treated yak pericardium is less damaged. The surface of serosa is smoother'and its glycoprotein coat incurs lessloss. The arrangements of collagen fiber make the material more elastic and extensible. The split degree of implanted epoxide-treated yak perlcardium is lower than that of implanted glutaraldehyde-treated yak Pericardium.These suggest that the mechanical property of epoxidetreated yak pericardium is superior to that of glutaraldehydetreated yak Pericardium, and the mechnical property of a material is determined by the arrangements of collagen fiber.

关 键 词：牦牛心包 环氧改性 戊二醛 生物瓣 扫描电镜 

分 类 号：R318.08[医药卫生—生物医学工程] R318.11[医药卫生—基础医学]