急性脑梗塞患者红细胞免疫功能与血清SOD、LPO的变化  

Red blood cell immune adherence with the dynimic changes of free radical metabolism in the acute cerebral infarct patients

作　　者：阎伟[1] 许二赫[1] 张昀[1] 

机构地区：[1]白求恩医大二院神经内科

出　　处：《中风与神经疾病杂志》1996年第4期211-212,共2页Journal of Apoplexy and Nervous Diseases

摘　　要：测定了３１例急性脑梗塞患者红细胞Ｃ３ｂ受体花环率（ＲＢＣ—Ｃ３ｂＲＲ）和红细胞免疫复合物花环率（ＲＢＣ—ＩＣＲ）以及可能影响红细胞免疫粘附（ＲＣＩＡ）功能的血清脂质过氧化物（ＬＰＯ）、超氧化物歧化酶（ＳＯＤ）。结果表明，急性脑梗塞患者ＲＢＣ—Ｃ３ｂＲＲ明显降低，而ＲＢＣ—ＩＣＲ明显增高；血清ＳＯＤ含量减少，ＬＰＯ明显增高。ＲＢＣ—Ｃ３ｂＲＲ降低与血清ＬＰＯ增高呈显著负相关，与ＳＯＤ呈正相关。上述结果说明红细胞免疫功能降低与体内自由基代谢改变有关。This paper detected the dynimic changes of the following four indexes in 31 cases with acute cerebral infarction. These indexes includes the red blood cell. C3breceptor rate(RBC-C3b RR), the red blood cell immune complex rate(RBC-ICR), serum lipid peroxide(LPO) which might affect the function of red blood cell immune adherence(RCIA). and superoxide dismutase(SOD). Results showed that the RBC-C3bRR was significantly lower,but RC-ICR higher in the acute cerebral infarct patients, simultaneously their serum SOD content decreased but that of LPO increased significantly. There were negative correlation between the decreasing of RBC-c3bRR with the increasing of serum LPO, correlation with SOD, Above results suggest that the decreasing of RBC immune reaction may relate with the changes of internal free radical metabolism.

关 键 词：脑梗塞 红细胞免疫 SOD LPO 

分 类 号：R743.330.3[医药卫生—神经病学与精神病学]