精神分裂症的阴性症状与脑血灌流量的相关研究  

A correlative study of negative symptoms and cerebral blood perfusion flow in schizophrenia.

作　　者：李星宝[1,2] 赵贵芳[1,2] 唐济生[1,2] 张伯全[1,2] 侯瑞华 张天亮[1,2] 王善信 宋绳禹[1,2] 吴志兴[1,2] 郭川流[1,2] 

机构地区：[1]山东省精神卫生中心 [2]山东省立医院核医学科

出　　处：《中国神经精神疾病杂志》1996年第6期342-345,共4页Chinese Journal of Nervous and Mental Diseases

基　　金：山东省青年科学基金

摘　　要：目的探讨精神分裂症患者脑血灌流量与阴性症状的关系。方法应用单光子发射计算机断层技术研究阴性症状为主和非阴性症状为主的精神分裂症患者各２５例的脑血灌流量，并与２１例正常对照组比较。结果发现两个研究组均存在额叶、颞叶及基底节脑血灌流量降低，但两组检测结果无差异；相关研究显示患者脑血灌流量与身高呈正相关性。结论精神分裂症的阴性症状与脑血灌流量降低无相关性。Objective To test the hypothesis that the cerebral blood perfusion flow (CBPF) correlates with negative symptoms in schizophrenia. Methods Twenty five schizophrenic patients with more negative symptoms, 25 cases with less negative symptoms and 21 normal controls were scanned with single photon emission computed tomography to measure their CBPF. Results It showed that there were lower CBPF in both more negative symptoms group and less negative symptoms group, but there was no difference of lower CBPF between the two groups. The lower CBPF focused on frontal lobe, temporal lobe and basal ganglia. The heights of patients significantly positively correlated with lower CBPF in some cerebral regions. Conclusions No significant correlation was found between negative symptoms and lower CBPF

关 键 词：精神分裂症 阴性症状 脑血灌流量 

分 类 号：R749.302[医药卫生—神经病学与精神病学]