无抽搐电休克治疗难治性精神分裂症临床观察  

Efficacy of modified electroconvulsive therapy in treatment-refractory schizophrenia

作　　者：易正辉[1] 徐庆华[2] 盛国红[2] 吴晓波[2] 吴国君[2] 

机构地区：[1]上海交通大学医学院精神医学教研室,201108 [2]上海市精神卫生中心

出　　处：《临床精神医学杂志》2006年第5期280-281,共2页Journal of Clinical Psychiatry

摘　　要：目的:了解无抽搐电休克治疗(MECT)对难治性精神分裂症的疗效与不良反应。方法:对39例难治性精神分裂症患者在原服用抗精神病药基础上合并MECT治疗,分别于合并治疗前后采用阳性与阴性症状量表(PANSS)及副反应量表(TESS),韦氏记忆量表(WMS)评定疗效及不良反应。结果:合并MECT后PANSS评分明显降低(P<0.01),WMS评分在治疗结束后1d明显降低,1周及2周时恢复。结论:MECT对难治性精神分裂症有效,不良反应少。Objective： To understand the efficacy and side effects of modified electroconvulsive therapy （MECT） in treatment-refractory schizophrenia. Method： 39 patients with TRS who had received antipsychotic medication were assigned to receive MECT, and the positive and negative syndrome scale （PANSS） ,treatment emergent symptoms scale （TESS） and Wechsler memory scale （WMS） were used before and after treatment. Results：The PANSS scores decreased significantly after MECT. The WMS scores decreased significantly at 1 day after the endpoint of MECT, but there was no significant difference between before and after 1,2 weeks of endpoint of MECT. Condusion：MECT was effective in TRS, and it had little side effects.

关 键 词：无抽搐电休克治疗 难治性精神分裂症 

分 类 号：R749.054[医药卫生—神经病学与精神病学]