子宫肌瘤导管栓塞治疗的临床疗效观察  

Curative effect of transcatheter embolization for uterine fibroids

作　　者：徐圣德[1] 张宇东[1] 高斌[1] 李华[1] 汪涛[1] 许国忠[1] 

机构地区：[1]安徽省合肥市第一人民医院介入放射科,安徽合肥230061

出　　处：《安徽医药》2006年第10期759-760,共2页Anhui Medical and Pharmaceutical Journal

摘　　要：目的评价经导管超选择子宫动脉栓塞（TUAE）治疗子宫肌瘤的临床疗效。方法对32例子宫肌瘤患者经导管于子宫动脉注入PVA微粒或海澡酸钠微球＋明胶海绵颗粒栓塞治疗，随访3～60个月，主要观察临床症状改善、肌瘤大小及子宫体积的变化，同时通过对栓塞后月经观察，部分病例激素水平的测定，了解栓塞后卵巢功能的变化。结果月经完全恢复正常占有89．7％（26／29），12例下腹部及腰腿胀痛和7例尿频尿急于栓后2周症状消失。21例贫血有17例基本恢复正常。栓塞后6个月肌瘤体积平均缩小64．2％，子宫体积平均缩小49．6％。5例卵巢内分泌功能测试栓塞前后变化无明显差异。结论TUAE是一项治疗子宫肌瘤安全、有效的治疗方法，远期疗效尚需进一步观察.Aim To evaluate the clinical effect of transcatheter uterine artery embolization（TUAE） as a treatment for uterine fibromyo- ma. Methods 32 cases of uterine fibroids were treated by TUAE using PVA or KMG and Gelfoam sponge paeticles. All patients were followed up from 3 to 60 months to observe the changes of fibroid volume and uterine volume. The changes of ovarian function after TUAE were found out by observation on menstruation and test of ovarian hormone. Results 26 out of 29 cases （ 89.7% ） with menorrhagia completely recovered;lumbago and lover abdominal pain in 12 cases disappeared two weeks after TUAE;the symptom of frequency and urgency of micturition in 7 cases relieved. Anemia was improved in 17 out of 21 cases. 6 months after TUAT, average volume of fibroid and uterine decrease by 64.2% and 49.6% respectively. There was no significant difference in ovarian hormon level before and after embolization in 5 cases. Conclusion Transcatheter uterine artery embolization is a new promising method of treating fibroids. It has safe and good clinical results. Further investigation is required to assess its long -term effect.

关 键 词：子宫肌瘤 介入学 放射学 栓塞 治疗学 治疗效果 

分 类 号：R737.33[医药卫生—肿瘤]