闭经患者的外周血淋巴细胞染色体观察  

Observation of peripheral blood lymphocyte chromosome for amenorrheal patients

作　　者：靳耀英[1] 张韫[1] 石玉惠[1] 梁海燕[2] 刘伟[1] 高福云[1] 刘国玲[1] 李忻[1] 

机构地区：[1]中日友好医院临床医学研究所,北京100029 [2]中日友好医院妇产科,北京100029

出　　处：《中日友好医院学报》2006年第5期267-269,273,共4页Journal of China-Japan Friendship Hospital

摘　　要：目的:探讨闭经患者与染色体异常的关系。方法:选择闭经患者139例(其中原发性闭经91例,继发性闭经48例),对其进行外周血淋巴细胞染色体检查。结果:原发闭经组,性染色体数目和(或)结构异常者28例,常染色体异常1例。继发闭经组,性染色体数目和(或)结构异常者4例,常染色体异常1例。结论:结合临床体征和染色体检查,不仅为闭经患者寻找病因提供理论依据,而且有利于指导闭经患者的治疗。Objective：To explore the relationship between amenorrhea and aberration of chromosome.Methods. One hundred and thirty nine patients were selected in the study,91 primary amenorrhea and 48 secondary amenorrhea.Each patient＇s chromosome karyotype of peripheral lymphocyte was analyzed.Results：There were 29 patients with abnormal sex chromosome number or structure among cases with primary amenorrhea,and 5 patients with abnormal sex chromosome number or structure among cases with secondary amenorrhea. Conclusion：Combined clinical examination with chromosome analyzing,we will not only find the reasons of amenorrhea,but also have practical meaning for the treatment.

关 键 词：原发闭经 继发闭经 染色体 染色体异常 核型分析 

分 类 号：R711.5[医药卫生—妇产科学]