原发性低颅压综合征15例临床分析及文献复习  

Clinical analysis of 15 cases of primary intracranial hypotension and review of reference

作　　者：张玉生[1] 徐仁伵[1] 吴裕臣[1] 

机构地区：[1]南昌大学第一附属医院神经内科,330006

出　　处：《卒中与神经疾病》2006年第5期287-289,共3页Stroke and Nervous Diseases

摘　　要：目的探讨原发性低颅压综合征(PIH)的临床特点、发病机制、脑脊液(CSF)及影像学改变。方法回顾性分析15例PIH患者的临床资料并复习文献。结果15例患者均有体位性头痛;CSF压力均小于70mmH2O,细胞数增高2例,蛋白增高9例;13例行头颅CT平扫,9例正常,2例双侧脑室系统缩小,1例慢性硬膜下血肿,1例硬膜下积液;9例行头颅MRI检查,4例硬脑膜增厚并明显强化,1例慢性硬膜下血肿,1例“脑下沉”改变。结论认识PIH的临床特点、发生机制、CSF及影像学特征,可提高PIH的确诊率;本病预后一般较好。Objective To investigate the clinical feat ures,pathogenesis and the changes of cerebrospinal fluid （CSF） and imageology in primary intracranial hypotension （PIH）. Methods To retrospectively analyse the clinical information of 15 cases of PIH and review the reference. Results Among them,all the patients had postural headache and CSF pressure is low to 70 mmH2O, cell counts was higher than the other patients in 2 cases, the protein of 9 cases increased, In 13 cases scaned by brain CT 9 cases were normal,2 cases had atrophy of bilateral cerebral ventricle system, 1 case had chronic subdural hematoma, 1 case had subdural collection of fluid. In 9 cases by brain MRI,4 cases were pachymeningeal thickening and post-contrast enhancement, 1 patient was chronic subdural hematoma, 1 patient was ＂sagging＂ of the brain. Conclusion The clinical features, pathogenesis and the features of CSE and imageology in PIH conduce to clinical diagnosis ratio. The PIH usually has a good recovery.

关 键 词：低颅压综合征 脑脊液 影像学 

分 类 号：R741[医药卫生—神经病学与精神病学]