氙CT评价颈内和大脑中动脉狭窄或闭塞的脑血流研究  

Study on cerebral blood flow in patients with ICA/MCA stenosis or occlusion by Xenon CT

作　　者：卢洁[1] 李坤成[1] 高艳[1] 焦立群[2] 李萌[2] 

机构地区：[1]首都医科大学宣武医院医学影像学部放射科,北京100053 [2]首都医科大学宣武医院医学影像学部神经外科,北京100053

出　　处：《中国医学影像技术》2006年第9期1317-1320,共4页Chinese Journal of Medical Imaging Technology

摘　　要：目的探讨颈内/大脑中动脉慢性狭窄、闭塞患者的氙CT脑血流成像表现及其临床应用价值。方法20例颈内/大脑中动脉慢性重度狭窄或闭塞患者行氙CT脑血流成像检查,2例行乙酰唑胺负荷试验。计算出脑血流图,进行定性和定量分析。结果20例颈内/大脑中动脉慢性重度狭窄或闭塞患者,10例单侧ICA/MCA重度狭窄或闭塞患者,7例发现病变侧CBF轻度下降,但无显著性差异(P>0.05)。10例单侧ICA/MCA闭塞,对侧重度狭窄患者,9例CBF图发现异常改变,表现为闭塞侧CBF下降较狭窄侧降低明显(P<0.05);闭塞侧CBF值与单侧病变患者的正常侧比较有显著性差异(P<0.05)。2例行乙酰唑胺负荷试验患者,负荷后CBF降低较负荷前明显。结论氙CT检查能够显示颈内/大脑中动脉慢性重度狭窄或闭塞脑血流情况,有利于临床的诊断和治疗。Objective To investigate the diagnostic value of XeCT in patients with ICA/MCA high-grade stenosis or occlusion. Methods XeCT was performed in 20 patients with ICA/MCA high-grade stenosis or occlusion. The cerebral blood flow （CBF） was measured, the qualitative and quantitative analysis were carried out on bilateral hemisphere. Results In 10 cases of unilateral ICA/MCA high-grade stenosis or occlusion, CBF changes corresponding to clinical symptoms were found in 7 cases, but the value of CBF had no statistical difference between affected side and contralateral side（P〉0.05）. In 10 cases of bilateral ICA/MCA high-grade stenosis or occlusion, CBF changes corresponding to clinical symptoms were found in 9 cases, the value of CBF had statistically significant difference between affected side and contralateral side（P〈0.05）. Conclusion XeCT could provide qualitative and quantitative changes of CBF in patients with bilateral ICA/MCA high-grade stenosis or occlusion and thereby it was helpful for the diagnosis and therapy.

关 键 词：颈内动脉 大脑中动脉 狭窄 闭塞 脑血流量 氙 体层摄影术 X线计算机 

分 类 号：R743.3[医药卫生—神经病学与精神病学] R814.42[医药卫生—临床医学]