光学相干层析成像技术用于裸鼠皮肤霉菌感染研究  

Study on Mildew Infecting Skin of Naked Mouse by Optical Coherence Tomography

作　　者：邵永红[1] 何永红[1] 马辉[1] 王淑霞[1] 张雅欧[1] 

机构地区：[1]清华大学深圳研究生院光学检测与成像实验室,北京518055

出　　处：《激光生物学报》2006年第5期536-539,共4页Acta Laser Biology Sinica

基　　金：广东省;深圳市科技计划项目(2005B16001149)

摘　　要：利用中心波长为850 nm的宽带光源SLD实现了纵向分辨率为8μm的光学相干层析成像系统。系统采用傅里叶域光学延迟线实现了深度扫描速度为160 mm/s,成像深度为3 mm。获得了裸鼠皮肤霉菌感染部位和健康皮肤的光学相干层析(optical coherence tom ography,OCT)图像,皮肤病变前后的内部结构信息清晰可见。An optical coherence tomography system with depth-resolution 8 μm and broadband source （SLD） is implemented. The depth scanning speed of 160 mm/s and imaging depth of 3 mm using Fourier-domain rapid scanning optical delay line has been used in the system. The OCT images of mildew infecting skin and healthy skin of nude mouse have been obtained. The structures of skin are shown in the images before the pathological changes and after.

关 键 词：光学相干层析 皮肤 霉菌感染 

分 类 号：R312[医药卫生—基础医学] R318.51